Results 31 to 40 of about 28,518 (238)

Mass Spectrometry Study of New Polyamine Derivatives of Caffeine

Acta Chimica Slovenica, 2018
The mass spectrometric fragmentations of ten new 8-alkylaminocaffeine derivatives were investigated. The fragmentation pathways of new polyamine derivatives of caffeine on the basis of low and high-resolution electron ionization (EI) mass spectra were ...
Arleta Sierakowska, Beata Jasiewicz, Tomasz Pospieszny   +2 more
doaj   +1 more source

1,2,3-Triazoles as leaving groups: SNAr reactions of 2,6-bistriazolylpurines with O- and C-nucleophiles

Beilstein Journal of Organic Chemistry, 2021
A new approach was designed for the synthesis of C6-substituted 2-triazolylpurine derivatives. A series of substituted products was obtained in SNAr reactions between 2,6-bistriazolylpurine derivatives and O- and C-nucleophiles under mild conditions. The
Dace Cīrule, Irina Novosjolova, Ērika Bizdēna, Māris Turks   +3 more
doaj   +1 more source

Shape‐Controlled Guanine Self‐Assemblies for Stable and Fast‐Ion Solid–Electrolyte Interphases in Sustainable Li Metal Batteries

Advanced Functional Materials, EarlyView.
The shape of guanine self‐assemblies is tuned by introducing alkyl (G8), fluoroalkyl (G8f), and oligoether (G8g) side chains into the G moiety. The scanning tunneling microscopy results and calculations show that the presence and type of the side chain strongly affect the G self‐assembly network.
So‐Huei Kang, So‐Dam Sohn, Kyung Min Lee, Seok‐Kyu Cho, Byongkyu Lee, Ji Eun Lee, Sang‐Young Lee, Sang Kyu Kwak, Hyung‐Joon Shin, Changduk Yang   +9 more
wiley   +1 more source

Versatile synthesis and biological evaluation of novel 3’-fluorinated purine nucleosides

Beilstein Journal of Organic Chemistry, 2015
A unified synthetic strategy accessing novel 3'-fluorinated purine nucleoside derivatives and their biological evaluation were achieved. Novel 3’-fluorinated analogues were constructed from a common 3’-deoxy-3’-fluororibofuranose intermediate.
Hang Ren, Haoyun An, Paul J. Hatala, William C. Stevens Jr, Jingchao Tao, Baicheng He   +5 more
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Evaluation of methodologies of urine collection to estimate microbial synthesis in bovines diets containing or not containing lipids

Bioscience Journal, 2020
This study investigated the effectiveness of the urine sample collection method in predicting the volume urinary and synthesis of microbial nitrogen. Eight fistulated steers were used with accessible rumens and kept in individual stalls.
Laila Cecília Ramos Bendia, Carlos Augusto de Alencar Fontes, Elizabeth Fonsêca Processi, Clóvis Carlos Silveira Filho, Cláudio Teixeira Lombardi, Paulo Roberto Silveira Pimentel, Ronaldo Lopes Oliveira, Leilson Rocha Bezerra, Tiago Cunha Rocha   +8 more
doaj   +3 more sources

Unraveling RNA contribution to the molecular origins of bacterial surface-enhanced Raman spectroscopy (SERS) signals

Scientific Reports
Surface-enhanced Raman spectroscopy (SERS) is widely utilized in bacterial analyses, with the dominant SERS peaks attributed to purine metabolites released during sample preparation.
Jun-Yi Chien, Yong-Chun Gu, Chia-Chen Chien, Chia-Ling Chang, Ho-Wen Cheng, Shirley Wen-Yu Chiu, Yeu-Jye Nee, Hsin-Mei Tsai, Fang-Yeh Chu, Hui-Fei Tang, Yuh-Lin Wang, Chi-Hung Lin   +11 more
doaj   +1 more source

Chemo-Enzymatic Generation of Highly Fluorescent Nucleoside Analogs Using Purine-Nucleoside Phosphorylase

Biomolecules
Chemo-enzymatic syntheses of strongly fluorescent nucleoside analogs, potentially applicable in analytical biochemistry and cell biology are reviewed. The syntheses and properties of fluorescent ribofuranosides of several purine, 8-azapurine, and etheno ...
Alicja Stachelska-Wierzchowska, Jacek Wierzchowski   +1 more
doaj   +1 more source

Effects of theophylline on ADCY5 activation-From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients.

PLoS ONE, 2023
We show the effects of the three purine derivatives, caffeine, theophylline, and istradefylline, on cAMP production by adenylyl cyclase 5 (ADCY5)-overexpressing cell lines.
Dirk Tänzler, Marc Kipping, Marcell Lederer, Wiebke F Günther, Christian Arlt, Stefan Hüttelmaier, Andreas Merkenschlager, Andrea Sinz   +7 more
doaj   +1 more source

Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection

Advanced Materials Interfaces, EarlyView.
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon, Kristen Dellinger, Shyam Aravamudhan   +2 more
wiley   +1 more source