Results 171 to 180 of about 72,751 (304)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

An integrated bioinformatics and machine learning approach to identifying biomarkers connecting parkinson's disease with purine metabolism-related genes. [PDF]

BMC Neurol
Wang Y, Wu D, Zheng M, Yang T.
europepmc   +1 more source

Gallic acid modulates purine metabolism and oxidative stress induced by ethanol exposure in zebrafish brain

, 2022
Samira Leila Baldin, Karolyne de Pieri Pickler, Ana Caroline Salvador de Farias, Henrique Teza Bernardo, Rahisa Scussel, Bárbara da Costa Pereira, Suzielen Damin Pacheco, Eduardo Ronconi Dondossola, Ricardo Andrez Machado‐de‐Ávila, Almir Gonçalves Wanderley, Eduardo Pacheco Rico   +10 more
openalex   +2 more sources

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone, Afroditi Tripyla, Melanie C. Scalise, Maria L. Balmer, Lia Bally, Dominik M. Meinel   +5 more
wiley   +1 more source

Multi-Omics Analysis Reveals Disturbances of Purine Metabolism and Glutamate Metabolism in the Hippocampus of Lipopolysaccharide-Induced Mouse Model of Depression. [PDF]

Brain Behav
Li WW, Xiao R, Chen XY, Pu JC, Chen JJ, Wang HY, Liu LX, Li D, Zhang YD, Li WX, Xie P.   +10 more
europepmc   +1 more source

Comparison of Teratogenic Action of Substances Related to Purine Metabolism in Mouse Embryos

, 1972
Takaaki Fujii, Hideo Nishimura
openalex   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Ultrasound irradiation activates purine metabolism and mitochondrial respiration via the MAPK signaling pathway in myotubes. [PDF]

Biochem Biophys Rep
Ma X, Maeshige N, Yamaguchi A, Fu Y, Xing J, Guo Q, Lin H, Lu F, Kondo H, Fujino H.   +9 more
europepmc   +1 more source

Salivary uric acid as a biomarker for noninvasive diagnosis of diseases associated with purine metabolism disorder and methods for its determination

M.E. Stolbikova, I.Z. Gaydukova, G.A. Sapozhnikov, O.B. Svetlova, M.M. Musiychuk, I.Yu. Diment   +5 more
openalex   +1 more source

Comprehensive Detection of Disorders of Purine and Pyrimidine Metabolism by HPLC with Electrospray Ionization Tandem Mass Spectrometry [PDF]

, 2006
S. Hartmann, Jürgen G. Okun, C. Schmidt, Claus‐Dieter Langhans, Sven F. Garbade, Peter Burgard, Dorothea Haas, Jörn Oliver Sass, William L. Nyhan, Georg F. Hoffmann   +9 more
openalex   +1 more source