Results 171 to 180 of about 61,638 (306)

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

Cell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi, Hengjie Wang, Shuai Zhu, Minjian Chen, Xuejiang Guo, Qiang Wang, Ling Gu   +6 more
wiley   +1 more source

Identification of molecular subtypes and a prognostic signature based on machine learning and purine metabolism-related genes in breast cancer. [PDF]

Medicine (Baltimore)
Huang W, Tang P, Mei J, Zhang Z, Lu G.
europepmc   +1 more source

Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential. [PDF]

Int J Mol Sci, 2023
Cicero AFG, Fogacci F, Di Micoli V, Angeloni C, Giovannini M, Borghi C.   +5 more
europepmc   +1 more source

Studies on Purine-Pyrimidine Metabolism (1)

, 1992
Kinya Hiroshige, Yasumasa Kunifuji, Masayuki Takasugi, Akio Kuroiwa   +3 more
openalex   +2 more sources

The Leaf Reticulate Mutant dov1 Is Impaired in the First Step of Purine Metabolism [PDF]

, 2012
Christian Rosar, Kerstin Kanonenberg, Arun Nanda, Michael Mielewczik, Andrea Bräutigam, Ondřej Novák, Miroslav Strnad, Achim Walter, Andreas P.M. Weber   +8 more
openalex   +1 more source

The metabolism of the purines in man

Experimental Biology and Medicine, 1910
L. B. Mendel, J. F. Lyman
openaire   +2 more sources

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E. [PDF]

Front Immunol
Zhang J, Zhang X, Wu R, Dong CS.
europepmc   +1 more source

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

Lnc-TPT1-AS1/CBP/ATIC Axis Mediated Purine Metabolism Activation Promotes Breast Cancer Progression. [PDF]

Cancer Sci
Zhang Y, Zhang H, Li M, Li Y, Wang ZR, Cheng W, Liu Y, Fang Z, Zheng A, Wang J, Ma F.   +10 more
europepmc   +1 more source