Results 171 to 180 of about 1,394,357 (370)

Proteome‐Wide Analysis of Human Deletions

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein deletions are frequent among both natural and pathogenic variations. Many of them are misclassified in variation databases and the literature. Nonsense‐mediated decay prevents the expression of many nucleotide deletions. Many variants classified as protein deletions are not expressed at all.
Haoyang Zhang, Xinning Luan, Mauno Vihinen   +2 more
wiley   +1 more source

PURINE METABOLISM

Journal of Biological Chemistry, 1929
A.A. Christman, E.C. Mosier
openaire   +1 more source

DIPG-17. DYSREGULATED PURINE METABOLISM IN A LETHAL CHILDHOOD BRAINSTEM TUMOR REVEALS NEW TREATMENT STRATEGIES WITH OLD DRUGS [PDF]

Ian Mersich, Sunny Congrove, Matthew J. Horchar, Román Cáceres, Janki Desai, Pankaj B. Desai, Larry Sallans, Julie Haines, Ranjith Menon, Charles B. Stevenson, Peter de Blank, Natasha Pillay‐Smiley, Trent R. Hummel, Ali Tavassoli, Angelo D’Alessandro, Timothy N. Phoenix, Biplab Dasgupta   +16 more
openalex   +1 more source

149 ENZYMES OF PURINE NUCLEOTIDE METABOLISM IN MATURE RAT BRAlN NEURONS IN CULTURE [PDF]

, 1988
S. Brosh, Oded Sperling, Yael Bromberg, Yechezkel Sidi   +3 more
openalex   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria

Nature Communications
Purines and their derivatives control intracellular energy homeostasis and nucleotide synthesis, and act as signaling molecules. Here, we combine structural and sequence information to define a purine-binding motif that is present in sensor domains of ...
Elizabet Monteagudo-Cascales, Vadim M. Gumerov, Matilde Fernández, Miguel A. Matilla, José A. Gavira, Igor B. Zhulin, Tino Krell   +6 more
doaj   +1 more source

CELL CULTURE MODELS FOR THE STUDY OF PURINE METABOLISM IN HUMAN PLACENTAL TISSUE: 167 [PDF]

, 1985
Kari O. Raivio, Kim Vettenranta
openalex   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

PURINE METABOLISM

Journal of Biological Chemistry, 1927
A.A. Christman, H.C. Eckstein
openaire   +1 more source