Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells. [PDF]
J Biol Chem, 2022 Kropotov A +13 more
europepmc +1 more source
Nonlinear Dynamics in the Binary DNA/RNA Coding Problem [PDF]
arXiv, 2001 The presence of low dimensional chaos in the protein secondary structures, using the binary coded $\alpha$-helices and $\beta$-sheet motifs, has been investigated. In order to analyse symbolic DNA/RNA sequences the assignment, based on the purine/pyrimidine and strong/wea k H - bond classification sheme, of binary numbers to the nucleotides was made ...
arxiv
Upfront Enzyme Replacement via Erythrocyte Transfusions for PNP Deficiency [PDF]
, 2021 Albert, Michael H +6 more
core +2 more sources
RESIDUAL PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY IN A NEW DUTCH PATIENT WITH PNP-DEFICIENCY AND CELLULAR IMMUNODEFICIENCY: 172 [PDF]
, 1985 Gert Rijksen +7 more
openalex +1 more source
Purine nucleoside phosphorylase as a target to treat age-associated lower urinary tract dysfunction. [PDF]
Nat Rev Urol, 2022 Birder LA, Jackson EK.
europepmc +1 more source
The bounded derived category of a poset [PDF]
arXiv, 2017 We introduce a new combinatorial condition on a subinterval of a poset P (a clamped subinterval) that allows us to relate the Auslander-Reiten quiver of the bounded derived category of P to that of the subinterval. Applications include the determination of when a poset is fractionally Calabi-Yau and the computation of the Auslander-Reiten quivers of ...
arxiv
Purine nucleoside phosphorylase deficiency associated with a fatal lymphoproliferative disorder. [PDF]
, 1981 Alan R. Watson +4 more
openalex +1 more source
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors. [PDF]
J Med Chem, 2023 Skácel J +21 more
europepmc +1 more source
, 2014 The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan +2 more
core
Investigation of α-deuterium kinetic isotope effects on the purine nucleoside phosphorylase reaction by the equilibrium-perturbation technique [PDF]
, 1989 Pertti Lehikoinen +2 more
openalex +1 more source