Results 71 to 80 of about 7,413 (205)
Phosphoserine phosphatase (PSP) catalyzes the final step of de novo L-serine biosynthesis—the hydrolysis of phosphoserine to serine and inorganic phosphate—in humans, bacteria, and plants.
Francesco Marchesani+5 more
doaj +1 more source
Purine-metabolising enzymes and apoptosis in cancer [PDF]
The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation.
Allegrini S.+4 more
core +1 more source
We describe an 11-month-old boy who presented with recurrent respiratory infections from 6 months of age. His elder sister died at 10 months with severe septicemia and meningitis. The boy had a mild motor delay.
Nikit Shah+5 more
doaj +1 more source
Purine-pyrimidine symmetry, determinative degree and DNA [PDF]
Various symmetries connected with purine-pyrimidine content of DNA sequences are studied in terms of the intruduced determinative degree, a new characteristics of nucleotide which is connected with codon usage. A numerological explanation of CG pressure is proposed. A classification of DNA sequences is given.
arxiv
Polymorphisme de la purine nucléoside phosphorylase érythrocytaire bovine [PDF]
La distribution de variants électrophorétiques de la purine nucléoside phosphorylase (N.P.) contrôlée par deux allèles NP.H et NP.L a été étudiée sur des hémolysats bovins appartenant à des populations autochtones de zébus ou de taurins (race Baoulé) et ...
Bambara, L., Quéval, Rémy
core
A UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases [PDF]
Efficient reaction monitoring is crucial for data acquisition in kinetic and mechanistic studies. However, for conversions of nucleosides to their corresponding nucleobases, as observed in enzymatically catalyzed nucleoside phosphorylation reactions, the
Giessmann, Robert T.+5 more
core +1 more source
The vanishing of self-extensions over n-symmetric algebras of quasitilted type [PDF]
A ring R satisfies the Generalized Auslander-Reiten Condition if any R-module M with no self-extensions in degrees higher than m must have projective dimension at most m. We prove that this condition is satisfied by all n-symmetric algebras of quasitilted type- a broad class of self-injective algebras where every module is periodic under the Nakayama ...
arxiv
Temperature and Tautomeric Effects in High-Resolution Oxygen 1s X-ray Photoelectron Spectroscopy of Purines and Pyrimidines [PDF]
Purines and pyrimidines, crucial building blocks in biological systems, have attracted significant interest across molecular physics, biochemistry, pharmacology, and chemistry. Extensive spectroscopies have been employed for characterization, while the temperature and potential tautomeric effects can complicate the interpretation of underlying physics ...
arxiv +1 more source
Purine Nucleoside Phosphorylase: Allosteric Regulation of a Dissociating Enzyme
Purine nucleoside phosphorylase (EC 2.4.2.1) from bovine spleen is a trimeric enzyme that readily dissociates to the monomer. Dilution of enzyme from 20 to 0.02 microgram of protein/ml is accompanied by a greater than 50-fold increase in the specific activity (vtrimer = 0.23 nmol/min/microgram; vmonomer = 12.5 nmol/min/micrograms).
T W, Traut, P A, Ropp, A, Poma
openaire +5 more sources
Schistosomiasis affects million people and its control is widely dependent on a single drug, praziquantel. Computational chemistry has led to the development of new tools that predict molecular properties related to pharmacological potential.
Jefferson A Rocha+9 more
doaj +1 more source