Results 181 to 190 of about 76,319 (326)

Disruption of the Purine Nucleotide Cycle [PDF]

, 1980
Richard L. Sabina, Judith L. Swain, Bernard M. Patten, Tetsuo Ashizawa, William E. O’Brien, Edward W. Holmes   +5 more
openalex   +1 more source

Pharmacological evaluation of non‐nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

British Journal of Pharmacology, Volume 182, Issue 19, Page 4693-4709, October 2025.
Background and purpose Traumatic brain injury (TBI) is considered to be a leading cause of mortality and disability worldwide. After TBI, innate immunity is rapidly activated in response to damage‐associated molecular patterns, such as ATP release, recognised by P2X7 receptors.
Inés Valencia, Andrea Pastor‐Martínez, Céline Decouty‐Pérez, Ana Belen Lopez‐Rodriguez, María Álvarez‐Rubal, Eva Ramos, Francesco Calzaferri, Jorge Zamorano‐Fernández, Javier Giner‐García, Alexis J. Palpán‐Flores, Víctor Rodríguez‐Domínguez, Javier Rodríguez de Cía, Borja J. Hernández‐García, Alejandro Romero, Cristóbal de los Ríos, Javier Egea   +15 more
wiley   +1 more source

Fluoride ion catalyzed alkylation of purines, pyrimidines, nucleosides and nucleotides using alkyl halides

, 1979
Kelvin K. Ogilvie, Serge L. Beaucage, Michael F. Gillen, Douglas W. Entwistle, Michael A. Quilliam   +4 more
openalex   +2 more sources

LOW ADENINE NUCLEOTIDE POOLS IN BLOOM'S SYNDROME MAY REFLECT A DEFECTIVE SALVAGE PURINE BIOSYNTHESIS: 126 [PDF]

, 1985
Héctor Martínez-Valdez, Thomas C. Long, Andrew J. Andres, Milton W. Taylor   +3 more
openalex   +1 more source

The AhR Is a Critical Regulator of the Pulmonary Response to Cannabis Smoke

The FASEB Journal, Volume 39, Issue 18, 30 September 2025.
AhR activation coordinates the pulmonary response to cannabis smoke. Inhalation of cannabis smoke disrupts epithelial integrity and promotes inflammation. AhR is activated by cannabis smoke and regulates cytoskeletal structure, detoxification, antioxidant, and immune pathways.
Emily T. Wilson, Roham Gorgani, Nicole S. Heimbach, Alexandra Bartolomucci, Thupten Tsering, Julia V. Burnier, David H. Eidelman, Carolyn J. Baglole   +7 more
wiley   +1 more source

Viral Reprogramming of Nucleotide Synthesis and Its Impact on Viral Infection. [PDF]

J Med Virol
Dsouza L, Yang Z.
europepmc   +1 more source

The purine nucleotide cycle. Studies of ammonia production and interconversions of adenine and hypoxanthine nucleotides and nucleosides by rat brain in situ.

, 1978
Vera Schultz, John M. Lowenstein
openalex   +1 more source

The Purine‐Nucleotide Cycle [PDF]

, 1980
Juan J. Aragón, John M. Lowenstein
openalex   +1 more source

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, Volume 8, Issue 9, September 2025.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis. [PDF]

J Biol Chem, 2015
Zhao H, Chiaro CR, Zhang L, Smith PB, Chan CY, Pedley AM, Pugh RJ, French JB, Patterson AD, Benkovic SJ.   +9 more
europepmc   +1 more source