Results 181 to 190 of about 661,667 (342)

Hyperuricemia and Gout as Metabolic Disorders, and Purine Nucleotide and Uric Acid Metabolism

, 2005
Jun Oka
openalex   +2 more sources

De novo synthesis of purine nucleotides in human peripheral blood leukocytes. Excessive activity of the pathway in hypoxanthine-guanine phosphoribosyltransferase deficiency.

Journal of Clinical Investigation, 1976
S. Brosh, P. Boer, B. Kupfer, A. de Vries, O. Sperling   +4 more
semanticscholar   +1 more source

How Plants May Maintain Protein Homeostasis Under Rising Atmospheric CO2

Plant, Cell &Environment, EarlyView.
ABSTRACT Vascular plants may employ several physiological mechanisms to stabilize their protein contents as atmospheric CO2 concentrations change over a day, year, decade, or century. One mechanism is that plants may rely more on soil ammonium as their nitrogen source when CO2 increases.
Arnold J. Bloom, Xiaoxiao Shi, Nathan M. Hannon   +2 more
wiley   +1 more source

Purine nucleotides induce regulated secretion of von Willebrand factor: involvement of cytosolic Ca2+ and cyclic adenosine monophosphate-dependent signaling in endothelial exocytosis.

Blood, 1998
Ulrich M. Vischer, Claes B. Wollheim
semanticscholar   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Structure-guided engineering of a polyphosphate kinase 2 class III from an <i>Erysipelotrichaceae</i> bacterium to produce base-modified purine nucleotides. [PDF]

RSC Chem Biol
Mitton-Fry RM, Rasche R, Lawrence-Dörner AM, Eschenbach J, Tekath A, Rentmeister A, Kümmel D, Cornelissen NV.   +7 more
europepmc   +1 more source

Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.

, 1994
Kelly A. Brayton, Z. Chen, Gaochao Zhou, Péter L. Nagy, Anthony Gavalas, Jeffrey M. Trent, Larry L. Deaven, Jack E. Dixon, H Zalkin   +8 more
openalex   +1 more source

Immunomodulatory purine nucleotides, not NAD+ depletion, are associated with TIR domain-mediated cell death

, 2023
Eastman, Samuel, Smith, Thomas, Clemente, Thomas, Guo, Ming   +3 more
openalex   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source