Results 111 to 120 of about 2,325,321 (255)

In Vitro Evidence for Oral Soft Tissue Regenerative Effects of a Polynucleotide–Hyaluronan Formulation

Clinical and Experimental Dental Research, Volume 11, Issue 6, December 2025.
ABSTRACT Objectives We aimed to investigate the effects of a polynucleotide–hyaluronan (PN–HA) formulation on human palatal fibroblasts (HPFs) and oral epithelial cells (OKF6/TERT‐2) to assess its potential application in oral soft tissue reconstructive procedures. Material and Methods The impact of PN–HA on cell viability, migration, and proliferation
Ina Mladenova, Xiaoqing Song, Cristina Nica, Anton Sculean, Maria B. Asparuhova   +4 more
wiley   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

Maestros of anesthesia

eLife
Microglia regulate anesthesia by altering the activity of neurons in specific regions of the brain via a purinergic receptor.
Romeesa Khan, Rodney M Ritzel
doaj   +1 more source

Purinergic Receptor

Definitions, 2020

semanticscholar   +1 more source

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

Glia, Volume 73, Issue 12, Page 2464-2482, December 2025.
Main Points Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz, Madison Doceti, JaQuinta Thomas, Abigayle Duffy, Morgan Coburn, Akhabue K. Okojie, Audrey Lee, Elizabeth Aidita Sou, Alban Gaultier, Ukpong B. Eyo   +9 more
wiley   +1 more source

Purinergic modulation of major depressive disorder: Experimental findings, pathogenesis and therapeutic opportunities

Pharmacological Research
Major depressive disorder (MDD) is a mental illness characterized primarily by persistent low mood and anhedonia. Traditional monoamine antidepressants have not achieved entirely satisfactory clinical efficacy.
Xing-Ying Ren, Patrizia Rubini, Tobias Engel, Yong Tang, Peter Illes   +4 more
doaj   +1 more source

Glycosides from edible sea cucumbers stimulate macrophages via purinergic receptors [PDF]

, 2016
Dmitry L. Aminin, Еvgeny А. Pislyagin, Maxim E. Astashev, A. A. Es’kov, Valery B. Kozhemyako, С. А. Авилов, Elena Zelepuga, Ekaterina A. Yurchenko, Leonid Kaluzhskiy, E. P. Kozlovskaya, Ivanov As, Valentin A. Stonik   +11 more
openalex   +1 more source

Morpho‐Histo‐Cytological Evaluation of Oral Tissues in Burning Mouth Syndrome: A Systematic Review

Journal of Oral Rehabilitation, Volume 52, Issue 12, Page 2449-2480, December 2025.
This systematic review on Burning Mouth Syndrome (BMS) included 14 studies that examined histological changes. 12 studies used incisional biopsies and 2 used exfoliative cytology. Histology and molecular biology techniques were used to assess morphological, phenotypical and genomic changes in oral tissues, primarily from the tongue.
André Luís Porporatti, Ângela Graciela Deliga Schroder, Ashley Lebel, Nathan Moreau, Annabelle Réaux‐Le Goazigo, Ihsène Taïhi, Heike Rittner, Tara Renton, Yves Boucher   +8 more
wiley   +1 more source

Purinergic P2X7 receptor expression increases in leukocytes from intra-abdominal septic patients

, 2023
Helios Martínez‐Banaclocha, Carlos García-Palenciano, L. Martínez‐Alarcón, J. Amores, Fatima Martín‐Sánchez, Giovanni A. Ercole, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Julio Padilla-Rodríguez, Alberto Baroja‐Mazo, Pablo Pelegrı́n, Juan José Martínez-García   +12 more
openalex   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, Volume 599, Issue 22, Page 3208-3243, November 2025.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source