Results 161 to 170 of about 2,316,796 (350)
The Journal of Physiology, EarlyView.Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener +2 more
wiley +1 more source
Purinergic receptors in multiple sclerosis pathogenesis
Brain Research Bulletin, 2019 Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, characterized by the presence of focal lesions in white and grey matter with peripheral immune cells infiltration. Purinergic receptors control immune cell function as well as neuronal and oligodendroglial survival, and the activation of astrocytes ...
Alazne Zabala +2 more
openaire +3 more sources
eLifeMicroglia regulate anesthesia by altering the activity of neurons in specific regions of the brain via a purinergic receptor.
Romeesa Khan, Rodney M Ritzel
doaj +1 more source
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Glia, Volume 73, Issue 10, Page 2003-2024, October 2025.Main Points Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2022 Adenosine triphosphate (ATP) initially attracted attention as a neurotransmitter, with much research conducted on the regulation of neurotransmission in the autonomic and central nervous systems.
Isao Matsuoka +2 more
doaj
Adrenergic Control of P2Y6 Receptor‐Dependent Phagocytosis in Rodent and Human Microglia
Glia, Volume 73, Issue 10, Page 2025-2034, October 2025.Main Points Adrenergic signaling through ADRB2 modulates phagocytosis in microglia Crosstalk between ADRB2 and P2Y6 receptors conserved in rodent and human microglia ADRB2 activation inhibits both P2Y6 function and gene expression ABSTRACT Microglia, the resident immune cells of the central nervous system (CNS), are in constant survey of their ...
Thomas Deluc +10 more
wiley +1 more source
Mitogenic Signaling by ATP/P2Y Purinergic Receptors in Astrocytes: Involvement of a Calcium-Independent Protein Kinase C, Extracellular Signal-Regulated Protein Kinase Pathway Distinct from the Phosphatidylinositol-Specific Phospholipase C/Calcium Pathway [PDF]
, 1999 Joseph T. Neary +5 more
openalex +1 more source
The Role of Peripheral N‐Methyl‐D‐Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review
European Journal of Pain, Volume 29, Issue 7, August 2025.ABSTRACT Background and Objective NMDA receptors, predominantly located in the central nervous system and known for their roles in synaptic plasticity and central sensitisation of pain and itch, are also expressed in peripheral sensory neurons. Emerging evidence suggests that peripheral NMDA receptors contribute to pathological pain and potentially ...
Ryusuke Tanaka +3 more
wiley +1 more source
Expression of Purinergic Receptor Channels and Their Role in Calcium Signaling and Hormone Release in Pituitary Gonadotrophs [PDF]
, 1996 Melanija Tomić +3 more
openalex +1 more source