Results 41 to 50 of about 117 (117)
The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation
Neurogastroenterology &Motility, EarlyView.Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner +4 more
wiley +1 more source
Purinergic receptors in multiple sclerosis pathogenesis
Brain Research Bulletin, 2019 Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, characterized by the presence of focal lesions in white and grey matter with peripheral immune cells infiltration. Purinergic receptors control immune cell function as well as neuronal and oligodendroglial survival, and the activation of astrocytes ...
Alazne Zabala +2 more
openaire +3 more sources
Neurogastroenterology &Motility, EarlyView.In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source
Burning Mouth Syndrome Underlying Factors: A Roadmap From a Network Perspective
Oral Diseases, EarlyView.ABSTRACT Objective To investigate the relationship between biological, psychological, and social factors underlying Burning Mouth Syndrome (BMS). Subjects and Methods A case (n = 40) and control (n = 42) study containing 80 variables was examined using two network models based on regularized partial correlations (n = 82).
Oscar Gabriel Castaño‐Joaqui +3 more
wiley +1 more source
Veterinary Dermatology, EarlyView.Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki +1 more
wiley +1 more source
Purinergic receptors and gastrointestinal secretomotor function [PDF]
Purinergic Signalling, 2008 Secretomotor reflexes in the gastrointestinal (GI) tract are important in the lubrication and movement of digested products, absorption of nutrients, or the diarrhea that occurs in diseases to flush out unwanted microbes. Mechanical or chemical stimulation of mucosal sensory enterochromaffin (EC) cells triggers release of serotonin (5-HT) (among other ...
openaire +3 more sources
Experimental Physiology, EarlyView.Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka +3 more
wiley +1 more source
Purinergic receptors in the endocrine and exocrine pancreas [PDF]
Purinergic Signalling, 2007 The pancreas is a complex gland performing both endocrine and exocrine functions. In recent years there has been increasing evidence that both endocrine and exocrine cells possess purinergic receptors, which influence processes such as insulin secretion and epithelial ion transport. Most commonly, these processes have been viewed separately.
openaire +4 more sources
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source