Results 21 to 30 of about 1,272,508 (252)

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake

open access: yesFrontiers in Pharmacology, 2021
The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake.
Vanni Caruso   +8 more
doaj   +1 more source

Purinergic Receptors in Ocular Inflammation [PDF]

open access: yesMediators of Inflammation, 2014
Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease. When inflammation affects the eye, it can produce severe disorders affecting the superficial and internal parts of the visual organ.
Ana Guzman-Aranguez   +3 more
openaire   +5 more sources

Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia: Roles of P2 receptors and CD39 in ATP-stimulated microglia

open access: yesFrontiers in Physiology, 2023
Adenosine triphosphate (ATP) and its metabolites drive microglia migration and cytokine production by activating P2X- and P2Y- class purinergic receptors.
Byeong J. Chun   +7 more
doaj   +1 more source

Alterations of Purinergic Receptors Levels and Their Involvement in the Glial Cell Morphology in a Pre-Clinical Model of Autism Spectrum Disorders

open access: yesBrain Sciences, 2023
Recent data suggest that defects in purinergic signalling are a common denominator of autism spectrum disorders (ASDs), though nothing is known about whether the disorder-related imbalance occurs at the receptor level.
Lidia Babiec   +5 more
doaj   +1 more source

Purinergic Receptors: Elucidating the Role of these Immune Mediators in HIV-1 Fusion

open access: yesViruses, 2020
Purinergic receptors are inflammatory mediators activated by extracellular nucleotides released by dying or injured cells. Several studies have described an important role for these receptors in HIV-1 entry, particularly regarding their activity on HIV-1
Tracey L. Freeman, Talia H. Swartz
doaj   +1 more source

Purinergic signaling in the peripheral vestibular system [PDF]

open access: yes, 2022
The inner ear comprises the cochlea and vestibular system, which detect sound and acceleration stimulation, respectively. The function of the inner ear is regulated by ion transport activity among sensory epithelial cells, neuronal cells, non-sensory ...
최재영, 김성헌
core   +1 more source

Purinergic signaling in infection and autoimmune disease

open access: yesBiomedical Journal, 2016
Purinergic signaling plays a key role in inflammatory processes and modulates immune responses against a variety of bacterial and eukaryotic parasites.
Luiz Eduardo Baggio Savio   +1 more
doaj   +1 more source

Traditional Chinese medicine alleviating neuropathic pain targeting purinergic receptor P2 in purinergic signaling: A review

open access: yesBrain Research Bulletin, 2023
Past studies have suggested that Chinese herbal may alleviate neuropathic pain, and the mechanism might target the inhibition of purinergic receptor P2.
Bo Yang, Nengwei Yu
doaj   +1 more source

Purine and purinergic receptors [PDF]

open access: yesBrain and Neuroscience Advances, 2018
Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors have been cloned and characterised. P1 receptors are selective for adenosine, a breakdown product of adenosine 5′-triphosphate after degradation by ...
openaire   +2 more sources

Purinergic signaling in the gastrointestinal tract [PDF]

open access: yes, 2011
Geoffrey Burnstock completed a BSc at King's College London and a PhD at University College London. He held postdoctoral fellowships with Wilhelm Feldberg (National Institute for Medical Research), Edith Bülbring (University of Oxford) and C.
Geoffrey Burnstock, Burnstock, G
core   +1 more source

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