Results 201 to 210 of about 32,234 (224)

Purinergic receptors in auditory neurotransmission

Hearing Research, 2003
The effects of ATP (adenosine 5' triphosphate) analogs on gross cochlear potentials and single primary afferent discharge properties were studied by intracochlear perfusion in anesthetized guinea pigs. ATP-gamma-S was most potent, with betagammamethylene-ATP and Bz-ATP being significantly less effective.
T, Sueta, B, Paki, A W, Everett, D, Robertson   +3 more
openaire   +2 more sources

Purinergic receptors in gastrointestinal inflammation

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2008
Purinergic receptors comprise a family of transmembrane receptors that are activated by extracellular nucleosides and nucleotides. The two major classes of purinergic receptors, P1 and P2, are expressed widely in the gastrointestinal tract as well as immune cells.
Vasantha L, Kolachala, Rahul, Bajaj, Meghana, Chalasani, Shanthi V, Sitaraman   +3 more
openaire   +2 more sources

PET Imaging of Purinergic Receptors

2020
Over the recent years, interest in the purinergic signaling system has sparked in the field of positron emission tomography (PET). Purinergic receptors play key roles in physiological and pathological processes, although the exact role in these processes is not always fully understood.
Janssen, Bieneke, Vugts, Danielle J., Windhorst, Albert D.   +2 more
openaire   +3 more sources

Purinergic receptors in psychiatric disorders

Neuropharmacology, 2016
Psychiatric disorders describe different mental or behavioral patterns, causing suffering or poor coping of ordinary life with manifold presentations. Multifactorial processes can contribute to their development and progression. Purinergic neurotransmission and neuromodulation in the brain have attracted increasing therapeutic interest in the field of ...
openaire   +2 more sources

The enteric purinergic P2Y1 receptor

Current Opinion in Pharmacology, 2006
Significant recent discoveries have shown that the P2Y(1) purinergic receptor subtype is expressed in the enteric nervous system and at intestinal neuromuscular junctions. Secretomotor neurons, which release vasoactive intestinal peptide at their junctions with intestinal secretory glands, express the P2Y(1) receptor.
openaire   +2 more sources

Purinergic and Glutamatergic Receptors on Astroglia

2014
Astroglial cells express many neurotransmitter receptors; the receptors to glutamate and ATP being the most abundant. Here, we provide a concise overview on the expression and main properties of astroglial glutamate receptors (ionotropic receptors represented by AMPA and NMDA subtypes) and metabotropic (mainly mGluR5 and mGluR3 subtypes) and ...
Verkhratsky, A, Burnstock, G
openaire   +3 more sources

Purinergic receptors.

Polish journal of pharmacology, 1997
The aim of the present paper was characterization of purinergic receptors specific for nucleotides (P2) and nucleosides (P1). Their subclassification, distribution and functions have been briefly described.
openaire   +1 more source

Drooling Over Purinergic Receptors

Science Signaling, 2009
ATP stimulates fluid secretion in mouse salivary glands through the P2X 7 receptor.
openaire   +1 more source

Purinergic Receptor-Mediated Cytotoxicity

2006
Mitochondria are vitally important for maintaining cellular integrity. Calcium is considered a mediator of necrosis as well as a main cause of damage in isolated mitochondria. Our results show that mitochondrial Ca2+ regulation in hepatocytes is affected when [Ca2+]i is increased; this is followed by mitochondrial dysfunction and irreversible cell ...
J. Fred Nagelkerke, J. Paul Zoeteweij
openaire   +1 more source

Platelet ADP/Purinergic Receptors

1997
Platelet aggregation by adenosine 5′-diphosphate (ADP) plays a key role in the development and extension of arterial thrombosis. ADP has also been implicated in vascular smooth muscle cell proliferation leading to restenosis at sites of vascular injury (Crowley et al. 1994).
C. Gachet, J.-P. Cazenave
openaire   +1 more source