Extracellular purines in lung endothelial permeability and pulmonary diseases
The purinergic signaling system is an evolutionarily conserved and critical regulatory circuit that maintains homeostatic balance across various organ systems and cell types by providing compensatory responses to diverse pathologies.
Evgenia Gerasimovskaya+9 more
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The bumpy road of purinergic inhibitors to clinical application in immune-mediated diseases
Purinergic signaling plays important roles throughout the body in the regulation of organ functions during and following the disruption of homeostasis. This is also reflected by the widespread expression of two families of purinergic receptors (P1 and P2)
Matthias T Wyss+2 more
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Purinergic signaling in the gastrointestinal tract [PDF]
James J. Galligan
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Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters [PDF]
Cinzia Volonté, Nadia D’Ambrosi
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Purinergic signaling mediates neuroglial interactions to modulate sighs. [PDF]
Severs LJ+8 more
europepmc +1 more source
Unresolved issues and controversies in purinergic signalling [PDF]
Geoffrey Burnstock
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Trichomoniasis immunity and the involvement of the purinergic signaling
Innate and adaptive immunity play a significant role in trichomoniasis, the most common non-viral sexually transmitted disease worldwide. In the urogenital tract, innate immunity is accomplished by a defense physical barrier constituted by epithelial ...
Camila Braz Menezes, Tiana Tasca
doaj
Editorial: Therapy resistance in tumor microenvironment: metabolic reprogramming and purinergic signaling. [PDF]
Zanoni M, Borges da Silva H, Adinolfi E.
europepmc +1 more source
Modulation of purinergic signaling by NPP-type ectophosphodiesterases
Cristiana Stefan+2 more
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