Results 121 to 130 of about 26,356 (209)

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, Volume 7, Issue 4, August 2026.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Physiological mechanisms and therapeutic targets in chronic cough

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
James C. Brown, Katherine L. Rhatigan, Oliver J. Price, Peter S. P. Cho   +3 more
wiley   +1 more source

Light‐Activated Communication Between Synthetic and Living Cells via Photoresponsive Membranes

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Light‐triggered membrane rupture of SCs enables controlled release of adenosine triphosphate (ATP) and histamine, which activate purinergic and histaminergic signaling in HeLa cells, leading to intracellular Ca2+ mobilization. This biomimetic communication platform provides a simple strategy for engineering remotely controlled chemical signaling ...
Roberto Barbaro, Paola Albanese, Matilde Colella, Davide Lattarulo, Samrat Saha, Jack L.‐Y. Chen, Fabio Mavelli, Federico Rossi, Emiliano Altamura   +8 more
wiley   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Chronic spontaneous urticaria treatments and purinergic signaling: a therapeutic possibility. [PDF]

J Mol Med (Berl)
Fontana M, Simões JLB, de Carvalho Braga G, Fontana M, Filho JCM, Bagatini MD.   +5 more
europepmc   +1 more source

The purinergic signaling interfaces in breast cancer angiogenesis. [PDF]

Purinergic Signal
da Silva FC, Stabile J, Fürstenau CR, Araújo TG.   +3 more
europepmc   +1 more source

Purinergic Signaling at the Crossroads of Inflammation, Microbiota, and Intestinal Fibrosis. [PDF]

Cell Mol Gastroenterol Hepatol
Shou J, Fu T.
europepmc   +1 more source

Purinergic signaling in dengue infection: modulation of P2 receptors as a potential therapeutic strategy. [PDF]

Purinergic Signal
de Melo VC, de Oliveira KI, Kipper M, Bagatini MD, da Silva GB.   +4 more
europepmc   +1 more source

Purinergic signaling modulates endothelial-to-mesenchymal transition in human aortic valve endothelial cells. [PDF]

BBA Adv
Schmidt V, Weber A, Lichtenberg A, Schrader J, Martsch P, Barth M, Akhyari P.   +6 more
europepmc   +1 more source