Results 111 to 120 of about 4,754,967 (333)
Delineating Purinergic Signaling in Drosophila
International Journal of Molecular Sciences, 2022 Simplistic models can aid in discovering what is important in the context of normal and pathological behavior. First recognized as a genetic model more than 100 years ago, to date, fruit flies (Drosophila melanogaster) still remain an astonishingly good laboratory stand-in for scientists to study development and physiology and to investigate the ...
Cinzia Volonte' +3 more
openaire +2 more sources
Memorias do Instituto Oswaldo Cruz, 2015 Trichomonas vaginalis is a flagellate protozoan that parasitises the urogenital human tract and causes trichomoniasis. During the infection, the acquisition of nutrients, such as iron and purine and pyrimidine nucleosides, is essential for the survival ...
Muriel Primon-Barros +7 more
doaj +1 more source
Recovery of Graph Signals from Sign Measurements [PDF]
arXiv, 2021 Sampling and interpolation have been extensively studied, in order to reconstruct or estimate the entire graph signal from the signal values on a subset of vertexes, of which most achievements are about continuous signals. While in a lot of signal processing tasks, signals are not fully observed, and only the signs of signals are available, for example
arxiv
Understanding the role of P2X7 in affective disorders—are glial cells the major players? [PDF]
, 2015 Pathophysiology associated with several psychiatric disorders has been linked to inflammatory biomarkers. This has generated a theory of major depressive disorders as an inflammatory disease.
Jenkins, Trisha A. +2 more
core +5 more sources
Environmental Toxicology and Chemistry, EarlyView.Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
ATP as a presynaptic modulator [PDF]
, 2000 © 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
core +1 more source
Glia, EarlyView.ABSTRACT Aquaporin‐4 (AQP4) is a water‐selective channel expressed in glial cells throughout the central nervous system (CNS). It serves as the primary water channel in the neuropil and plays roles in physiological functions, including regulating water homeostasis by adjusting cell volume and modulating neuronal activity. Different isoforms of AQP4 are
Donatella Lobraico +8 more
wiley +1 more source
Topological Signal Processing over Simplicial Complexes [PDF]
, 2019 The goal of this paper is to establish the fundamental tools to analyze signals defined over a topological space, i.e. a set of points along with a set of neighborhood relations. This setup does not require the definition of a metric and then it is especially useful to deal with signals defined over non-metric spaces.
arxiv +1 more source
Purinergic Signaling in Pulmonary Inflammation [PDF]
Frontiers in Immunology, 2019 Purine nucleotides and nucleosides are at the center of biologic reactions. In particular, adenosine triphosphate (ATP) is the fundamental energy currency of cellular activity and adenosine has been demonstrated to play essential roles in human physiology and pathophysiology.
Holger K. Eltzschig +6 more
openaire +4 more sources
Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]
, 2019 Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura +8 more
core +1 more source