Results 11 to 20 of about 246,268 (219)
Purinergic signalling in bone [PDF]
Frontiers in Endocrinology, 2012 Purinergic signalling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells.
Robin Mark Howard Rumney +3 more
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Purinergic signalling and diabetes [PDF]
Purinergic Signalling, 2013 The pancreas is an organ with a central role in nutrient breakdown, nutrient sensing and release of hormones regulating whole body nutrient homeostasis. In diabetes mellitus, the balance is broken—cells can be starving in the midst of plenty.
Ivana Novak +5 more
core +5 more sources
Purinergic signalling in neuroregeneration
Neural Regeneration Research, 2015 Purinergic signalling, adenosine 5′-triphosphate (ATP) as an extracellular signalling molecule, was proposed in 1972 (Burnstock, 1972). However, it was not generally accepted until the early 1990s when receptors for ATP and its breakdown product adenosine were cloned and characterised (Ralevic and Burnstock, 1998).
Geoffrey Burnstock
doaj +4 more sources
The involvement of purinergic signalling in obesity. [PDF]
Purinergic Signal, 2018 Obesity is a growing worldwide health problem, with an alarming increasing prevalence in developed countries, caused by a dysregulation of energy balance.
Burnstock G, Gentile D.
europepmc +7 more sources
Purinergic signalling in B cells [PDF]
Acta Biochimica Polonica, 2018 Adenosine and adenosine triphosphate are involved in purinergic signalling which plays important role in control of immune system. Much data have been obtained regarding impact of purinergic signalling on dendritic cells, macrophages, monocytes and T ...
Tadeusz Pawełczyk +5 more
core +4 more sources
Purinergic signalling: past, present and future [PDF]
Brazilian Journal of Medical and Biological Research, 2009 The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock
doaj +1 more source
Purinergic Signalling in the Cochlea. [PDF]
Int J Mol Sci, 2022 The mammalian cochlea is the sensory organ of hearing with a delicate, highly organised structure that supports unique operating mechanisms. ATP release from the secretory tissues of the cochlear lateral wall (stria vascularis) triggers numerous physiological responses by activating P2 receptors in sensory, supporting and neural tissues.
Vlajkovic SM, Thorne PR.
europepmc +3 more sources
Editorial: purinergic signalling-perspectives from Australia and New Zealand. [PDF]
Purinergic Signal, 2022 Sluyter R, Cederholm JME, Vlajkovic SM.
europepmc +2 more sources
Purinergic Signaling in Neuroinflammation [PDF]
International Journal of Molecular Sciences, 2021 ATP is stored in millimolar concentrations within the intracellular medium but may be released to extracellular sites either through the damaged plasma membrane or by means of various transporters [...]
Dmitry Aminin, Peter Illes
openaire +3 more sources
Purinergic signaling in the peripheral vestibular system [PDF]
, 2022 The inner ear comprises the cochlea and vestibular system, which detect sound and acceleration stimulation, respectively. The function of the inner ear is regulated by ion transport activity among sensory epithelial cells, neuronal cells, non-sensory ...
최재영, 김성헌
core +1 more source