Results 71 to 80 of about 4,754,967 (333)

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz, BD Gill, C Crawford, Claire M. Peppiatt-Wildman, DR Ferguson, DR Schneider, EM Schwiebert, EW Inscho, EW Inscho, FQ Yang, G Burnstock, G Burnstock, G Burnstock, G Manfredi, G Xu, HA Neufeld, HA Praetorius, HA Praetorius, Hardyal S. Gill, HM Liebich, I Kugelgen von, I Kugelgen von, J Czarnecka, James Malone-Lee, JC Mathies, Jennifer C. Jacoby, JM Buescher, JO Svensson, JR Gever, K Sugaya, Kevin M. G. Taylor, KH Schram, KR Kim, LA Birder, LC Rump, LD Todorov, M Cichna, M Katayama, MA Bailey, N Ozer, N Yamaoka, NS Zur, P Bodin, P Vinas, PD Wilson, R Corriden, RC Calvert, Rebecca E. Birch, RL Cordell, S Tatur, S Wiener, SA Levesque, Scott S. P. Wildman, Toby S. Scott-Ward, V Jankowski, V Kumar, W Yu, Y Cheng, Y Sun, Y Sun, Y Zheng   +60 more
core   +2 more sources

Purinergic Signaling in the Hallmarks of Cancer [PDF]

Cells, 2020
Cancer is a complex expression of an altered state of cellular differentiation associated with severe clinical repercussions. The effort to characterize this pathological entity to understand its underlying mechanisms and visualize potential therapeutic strategies has been constant.
Anaí del Rocío Campos-Contreras, Mauricio Díaz-Muñoz, Francisco G. Vázquez-Cuevas   +2 more
openaire   +4 more sources

Reversible Joint Hilbert and Linear Canonical Transform Without Distortion [PDF]

IEEE Transactions on Signal Processing, Volume 61, Issue 19, Oct.1, 2013, 2017
Generalized analytic signal associated with the linear canonical transform (LCT) was proposed recently by Fu and Li ["Generalized Analytic Signal Associated With Linear Canonical Transform," Opt. Commun., vol. 281, pp. 1468-1472, 2008]. However, most real signals, especially for baseband real signals, cannot be perfectly recovered from their ...
arxiv   +1 more source

A Systematic Review of the Expression, Signalling and Function of P2 Receptors in Primary Bone Cancer

Frontiers in Bioscience-Landmark, 2022
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall, Dan C Gagui, Victoria L Tippett, Norain B Ab Latif, Karan M Shah, Alison Gartland   +5 more
doaj   +1 more source

Signal Structure of the Starlink Ku-Band Downlink [PDF]

, 2022
We develop a technique for blind signal identification of the Starlink downlink signal in the 10.7 to 12.7 GHz band and present a detailed picture of the signal's structure. Importantly, the signal characterization offered herein includes the exact values of synchronization sequences embedded in the signal that can be exploited to produce pseudorange ...
arxiv   +1 more source

In situ imaging reveals properties of purinergic signalling in trigeminal sensory ganglia in vitro. [PDF]

Purinergic Signal, 2017
Nowodworska A, van den Maagdenberg AMJM, Nistri A, Fabbretti E.   +3 more
europepmc   +2 more sources

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma, Kennedy, Charles, Tasker, Paul N., Westfall, Timothy D.   +3 more
core   +1 more source

Transient signal generation in a self-assembled nanosystem fueled by ATP [PDF]

, 2015
A fundamental difference exists in the way signal generation is dealt with in natural and synthetic systems. While nature uses the transient activation of signalling pathways to regulate all cellular functions, chemists rely on sensory devices that ...
Pezzato, Cristian, Prins, LEONARD JAN
core   +2 more sources

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas, Eason, Robert, Wall, Mark J.   +2 more
core   +3 more sources

Purinergic signaling in kidney disease [PDF]

Kidney International, 2017
Nucleotides are key subunits for nucleic acids and provide energy for intracellular metabolism. They can also be released from cells to act physiologically as extracellular messengers or pathologically as danger signals. Extracellular nucleotides stimulate membrane receptors in the P2 and P1 family. P2X are ATP-activated cation channels; P2Y and P1 are
Robert J. Unwin, Robert J. Unwin, Robert I. Menzies, Frederick W.K. Tam, Matthew A. Bailey   +4 more
openaire   +7 more sources