Results 81 to 90 of about 6,124 (266)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

SCPL-TD3: An Intelligent Evasion Strategy for High-Speed UAVs in Coordinated Pursuit-Evasion

open access: yesDrones
The rapid advancement of kinetic pursuit technologies has significantly increased the difficulty of evasion for high-speed UAVs (HSUAVs), particularly in scenarios where two collaboratively operating pursuers approach from the same direction with ...
Xiaoyan Zhang   +5 more
doaj   +1 more source

PURSUIT-EVASION DIFFERENTIAL GAMES WITH THE GRÖNWALL TYPE CONSTRAINTS ON CONTROLS

open access: yesUral Mathematical Journal, 2020
A simple pursuit-evasion differential game of one pursuer and one evader is studied. The players' controls are subject to differential constraints in the form of the integral Grönwall inequality.
Bahrom T. Samatov   +2 more
doaj   +1 more source

Two-Dimensional Pursuit-Evasion in a Compact Domain with Piecewise Analytic Boundary

open access: yes, 2015
In a pursuit-evasion game, a team of pursuers attempt to capture an evader. The players alternate turns, move with equal speed, and have full information about the state of the game.
Beveridge, Andrew, Cai, Yiqing
core  

Visibility maintenance via controlled invariance for leader-follower Dubins-like vehicles [PDF]

open access: yes, 2010
The paper studies the visibility maintenance problem (VMP) for a leader-follower pair of Dubins-like vehicles with input constraints, and proposes an original solution based on the notion of controlled invariance.
Bullo, Francesco   +2 more
core  

Pursuit evasion on infinite graphs

open access: yesTheoretical Computer Science, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Heuristics for the Multi-Robot Worst-Case Pursuit-Evasion Problem

open access: yesIEEE Access, 2017
There is a growing demand for the use of robots to assist humans in their tasks, especially those involving risks, such as search and rescue. For this reason, coordination among several robots has been a common option, and one of the ways to study and ...
Livia Gregorin   +4 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Pursuit-evasion Game

open access: yes, 2007
In Pursuit-Evasion Games (PEGs) multiple robots (the pursuers) collectively determine the location of one or more evaders, and try to corral them. The game terminates when every evader has been corralled by one or more robots. PEGs have motivated interesting research directions in multi-robot coordination. Pursuers may not have line-of-sight visibility
Vieira, Marcos   +4 more
openaire   +1 more source

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