Results 91 to 100 of about 35,915 (205)

Evaluation of disease patterns, treatment and prognosis of tuberculosis in AIDS patient

open access: yesBrazilian Journal of Infectious Diseases, 2002
Patterns of disease, diagnosis, treatment and prognosis of tuberculosis in 100 patients co-infected with AIDS at Casa da AIDS clinic was studied. Demographic characteristics were as follows: 76 male patients, 24 female patients, 67 caucasian, average 35 ...
Atomiya Angela Naomi   +2 more
doaj  

Comparison of Pyrazinamide with Isoniazid for Their Effects on the Heme Biosynthetic Pathway in Mouse Liver

open access: yesMetabolites
Background/Objectives: Isoniazid (INH) and pyrazinamide (PZA) are first-line drugs used to treat tuberculosis (TB), but their use is generally contraindicated in patients with porphyria, a group of metabolic disorders caused by defects in the heme ...
Fu-Ying Qin   +6 more
doaj   +1 more source

Substituted N-(Pyrazin-2-yl)benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies

open access: yesMolecules, 2019
We prepared a series of substituted N-(pyrazin-2-yl)benzenesulfonamides as an attempt to investigate the effect of different linkers connecting pyrazine to benzene cores on antimicrobial activity when compared to our previous compounds of amide or retro ...
Ghada Bouz   +10 more
doaj   +1 more source

Short-course chemotherapy of pulmonary tuberculosis [PDF]

open access: yes, 1982
The last four decades have seen spectacular developments in the management of pulmonary tuberculosis. The discovery of streptomycin in 1943 by Waksman was soon followed by other drugs with anti-tuberculosis activity, such as PAS, isoniazid, pyrazinamide,
Tripathy, S P
core  

The Unusual Adverse Effects of Antituberculosis Therapy in Kidney Patients

open access: yesInternational Journal of Mycobacteriology
Background: Chronic kidney disease (CKD) patients are at a high risk of tuberculosis (TB), with a relative risk of developing active TB of 10%–25%.
Abdullah   +8 more
doaj   +1 more source

Methods for the estimation of pyrazinamide and pyrazinoic acid in body fluids [PDF]

open access: yes, 1980
zinoic acid in urine using an anion-exchange resin (Dowex-1) have been described. Recoveries were quantitative, and the sensitivity was 5 μg/ml for ail 3 estimations. In serum, pyrazinoic acid at a concentration of 50 μg/ml did not interfere with the
Gurumurthy, Prema   +2 more
core  

Cutaneous tuberculosis (scrofuloderma) in a five year-old boy: Case report [PDF]

open access: yes, 2009
Cutaneous tuberculosis (CTB) is a rare form of extrapulmonary TB in our region. The incidence of CTB seems to be increasing in some countries. CTB continues to be one of the most elusive and difficult diagnoses to make for dermatologists practicing in ...
Dehghan, M.   +2 more
core  

Lupus Vulgaris in a Maltese patient [PDF]

open access: yes, 2004
Introduction The incidence of cutaneous tuberculosis (TB) in the developed world has fallen, in parallel with the decline of other forms of TB. Nevertheless cases still occur and their diagnosis may be difficult.
Boffa, Michael J.   +2 more
core  

Acute pharmacokinetics of first line anti-tuberculosis drugs in patients with Pulmonary Tuberculosis and in patients with Pulmonary Tuberculosis co-infected with HIV [PDF]

open access: yes, 2011
The aim of this study was to compare the pharmacokinetics of antituberculosis drugs in patients with pulmonary tuberculosis (PTB) and in patients with PTB and HIV during the first 24 h of treatment.
Hassan, Mogamat Shafick   +2 more
core  

Arthralgia in South Indian patients with pulmonary tuberculosis during treatment with pyrazinamide and rifampicin [PDF]

open access: yes, 1984
Arthralgia was the major adverse reaction encountered in a clinical trial of the treatment of pulmonary tuberculosis with three short-course regimens containing pyrazinamide in South Indian patients.
Acharyulu, G S   +10 more
core  

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