Results 101 to 110 of about 25,215 (206)

Thermodynamic Assessment of the Pyrazinamide Dissolution Process in Some Organic Solvents

Molecules
Pyrazinamide is a first line drug used for the treatment of tuberculosis, a pathology that caused the death of more than 1.3 million people in the world during 2022, according to WHO, being a drug of current interest due to its relevance in ...
Jesus Tovar-Amézquita, Cristian Rincón-Guio, Francy Elaine Torres-Suarez, Magda Melissa Florez, Claudia Patricia Ortiz, Fleming Martinez, Daniel Ricardo Delgado   +6 more
doaj   +1 more source

Evaluation of colorimetric methods using nicotinamide for rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis

, 2010
The direct detection of pyrazinamide resistance in Mycobacterium tuberculosis is sufficiently difficult so that many laboratories don't attempt it. Most pyrazinamide resistance is caused by mutations that inactivate the pyrazinamidase enzyme needed to ...
Yoslaine Milián, Lemus, Dihadenys, Madruga, Mariela, Anandi Martin, Madruga, M., Palomino, J. C., Palomino, Juan Carlos, Lemus, D., Martin, Anandi, Mirabal, Niuris C, Howard Takiff, Takiff, H., Sergio L. Yzquierdo, Van Der Stuyft, Patrick, Mirabal, N. C., Yzquierdo, S. L., Milian, Yoslaine, Ernesto Montoro, Echemendia, Miguel, Van der Stuyft, P., Milián, Y., Niuris C. Mirabal, Takiff, Howard, Dihadenys Lemus, Martin, A., Montoro, Ernesto, Echemendía, M., Mariela Madruga, Patrick Van der Stuyf, Miguel Echemendía, Juan Carlos Palomino, Montoro, E., Yzquierdo, Sergio L   +32 more
core   +1 more source

Cerebrospinal fluid pyrazinamide concentrations in children with tuberculous meningitis

, 1988
Cerebrospinal fluid pyrazinamide concentrations were determined by high pressure liquid chromatography in 53 samples from 13 children who had tuberculous meningitis complicated by increased intracranial pressure.
Donald P.R., Seifart H.
core  

Successful Sequential and Additive Drug Challenge With Rapid Oral Desensitization in Rifampicin-Induced Fever. [PDF]

Respirol Case Rep
Guo XY, Zois C.
europepmc   +1 more source

Analysis of the impact of national centralized volume-based procurement drug policy on the market dynamics of tuberculosis drugs. [PDF]

BMC Health Serv Res
Yang J, Yu X, Yao Y, Zhao W, Chen Y, Wang Z, Xu M.   +6 more
europepmc   +1 more source

[A severe side effect of antitubercular therapy: pyrazinamide induced thrombocytopenia].

, 2008
International audienceThe haematological side effects of antitubercular drugs are not well known. We report the observation of a patient who received Rifater for the treatment of pulmonary tuberculosis. After one month of treatment, he developed an acute
N'Guyen Huy Thuy, G., Berard, H., Legodec, J., Chouaid, C., Rocher, F., Roseau, J.-B.   +5 more
core  

Pyrazinamide susceptibility testing in <i>Mycobacterium tuberculosis</i>: impact of false-positive BD MGIT 960 results and added value of sequencing for accurate diagnosis in a low-MDR-TB-incidence context. [PDF]

Front Cell Infect Microbiol
Semenova T, Gonzalez G, Lechartier B, Sander P, von Garnier C, Schulthess B, Mazza-Stalder J, Greub G, Opota O.   +8 more
europepmc   +1 more source

Therapeutic drug monitoring of first-line anti-tuberculosis drugs: impact of dose modification on plasma drug concentrations in pulmonary and extrapulmonary tuberculosis. [PDF]

J Clin Tuberc Other Mycobact Dis
Alavandar A.
europepmc   +1 more source

Comparison of phenotypic and genotypic methods for pyrazinamide susceptibility testing with Mycobacterium tuberculosis

, 2000
Mycobacterium tuberculosis converts pyrazinamide to its active form by using the enzyme pyrazinamidase. This enzyme is coded for on the pncA gene, and mutations in the pncA gene result in absence of active enzyme, conferring resistance to the drug ...
Davies, A P, Gillespie, S H, Mitchison, D A, Billington, O J, McHugh, T D   +4 more
core