Results 71 to 80 of about 25,215 (206)

Pyrazinamide monoresistance in clinical isolates

open access: yes, 2013
Aim: To determine pyrazinamide (PZA) monoresistance in clinical isolates of Mycobacterium tuberculosis complex (MTBC) isolated in hospitals in and around ...
ÖZKÜTÜK, NURİ   +3 more
core   +1 more source

In Silico study of pyrazinamide derivatives in Mycobacterium tuberculosis PanD

open access: yes, 2020
Recent studies show the coupling of pyrazinoic acid in PanD from Mycobacterium tuberculosis, as the end goal of the pro-drug pyrazinamide. We have coupled pyrazinamide derivatives with PanD by means of docking and molecular dynamics, to evaluate the ...
Christian Aliaga Paucar   +3 more
core   +1 more source

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

open access: yesInfection and Drug Resistance, 2020
Jie Shi, Ruyue Su, Danwei Zheng, Yankun Zhu, Xiaoguang Ma, Shaohua Wang, Hui Li, Dingyong Sun Henan Province Center for Disease Control and Prevention, Zhengzhou, Henan Province, People’s Republic of ChinaCorrespondence: Jie Shi; Dingyong Sun Tel ...
Shi J   +7 more
doaj  

Coexisting Hepatic and Renal Dysfunction During Pulmonary Tuberculosis Treatment: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Anti‐tuberculosis therapy may rarely cause concurrent liver and kidney injury, with ANCA positivity suggesting immune involvement. This case highlights the importance of early recognition, treatment modification, and multidisciplinary care to prevent complications and ensure effective tuberculosis management.
Irfan Malik   +7 more
wiley   +1 more source

Eur Respir J [PDF]

open access: yes
Pyrazinamide is a potent sterilising agent that shortens the treatment duration needed to cure tuberculosis. It is synergistic with novel and existing drugs for tuberculosis.

core  

Inhibition of probenecid uricosuria by pyrazinamide and para-aminohippurate

open access: yes, 1977
Both para-aminohippurate (PAH) and pyrazinamide inhibited the uricosuric response to probenecid administration. The mechanism of this inhibition of probenecid uricosuria was assessed in 18 male subjects.
H. S. Diamond, A. D. Meisel
core   +1 more source

Molecular Structure of Pyrazinamide: a Critical Assessment of Modern Gas Electron Diffraction Data from Three Laboratories

open access: yes, 2020
Accuracy and precision of molecular parameters determined by modern gas electron diffraction methodhave been investigated. Diffraction patterns of gaseous pyrazinamide have been measured independently in three laboratories, in Bielefeld (Germany ...
Timo, Glodde   +4 more
core   +1 more source

Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides

open access: yesMolecules, 2015
A series of N-alkyl-3-(alkylamino)pyrazine-2-carboxamides and their N-alkyl-3-chloropyrazine-2-carboxamide precursors were prepared. All compounds were characterized by analytical methods and tested for antimicrobial and antiviral activity.
Lucia Semelkova   +11 more
doaj   +1 more source

Effect of Carum carvi, a herbal bioenhancer on pharmacokinetics of antitubercular drugs: A study in healthy human volunteers

open access: yesPerspectives in Clinical Research, 2014
Aim and Objectives: The present study was undertaken in 20 healthy human volunteers to evaluate the effect of a herbal bioenhancer, Carum carvi on pharmacokinetics of rifampicin, isoniazid, and pyrazinamide in fixed dose combination (FDC).
Naiyma Choudhary   +4 more
doaj   +1 more source

Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

open access: yes
JEADV Clinical Practice, Volume 5, Issue 2, Page 678-681, June 2026.
Miranda K. Branyiczky   +6 more
wiley   +1 more source

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