Results 51 to 60 of about 35,915 (205)

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]

open access: yes, 2012
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Alfredo Ponce-de-Leon   +72 more
core   +9 more sources

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp   +6 more
wiley   +1 more source

Pyrazinamide-induced maculopapular rash

open access: yesIndian Journal of Dermatology, 2010
Pyrazinamide is a commonly used first-line antitubercular drug. Gastric-related adverse drug reactions are common with pyrazinamide. Dermatological manifestations due to pyrazinamide are rare.
Khayyam Khalid   +4 more
doaj  

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance. [PDF]

open access: yes, 2019
INTRODUCTION: 2018 World Health Organization (WHO) guidelines for the treatment of isoniazid (H)-resistant (Hr) tuberculosis recommend a four-drug regimen: rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx), with or without H ([H]RZE-
Abbara, A   +38 more
core   +4 more sources

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu   +11 more
wiley   +1 more source

A novel inexpensive electrochemical sensor for pyrazinoic acid as a potential tool for the identification of pyrazinamide-resistant Mycobacterium tuberculosis

open access: yesInternational Journal of Mycobacteriology, 2018
Introduction: Tuberculosis (TB) is a significant cause of morbidity and mortality worldwide. The patient compliance with the long treatment regimens is essential for successful eradication.
Daniel Rueda   +8 more
doaj   +1 more source

Secondary Tuberculosis of Tonsil case report and literature review [PDF]

open access: yes, 2012
A case report of secondary tuberculosis of tonsil is being discussed along with review of published literature. This report attempts to draw attention to the fact that Tuberculosis is resurgentdespite excellent chemotherapeutic drugs available.
Ramamoorthy, Geetha   +2 more
core   +1 more source

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]

open access: yes, 2010
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim   +70 more
core   +1 more source

Destroyed Lung Syndrome—A Devastating and Neglected Consequence of Pulmonary Tuberculosis: Case Series From a Low‐Resource Setting in Ghana

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Post‐pulmonary TB destroyed lung syndrome. ABSTRACT Tuberculous destroyed lung syndrome is a devastating and often neglected sequela of pulmonary tuberculosis. It has significant adverse effects on the quality of life of affected patients. This case series aims to raise awareness among clinicians and to emphasize the need for multifaceted preventive ...
Prosper Adjei   +7 more
wiley   +1 more source

Phenotypic and genotypic characterization of Mycobacterium tuberculosis pyrazinamide resistance—India, 2018–2020

open access: yesFrontiers in Microbiology
Pyrazinamide (PZA) is a key first-line antituberculosis drug that plays an important role in eradicating persister Mycobacterium tuberculosis (TB) bacilli and shortening the duration of tuberculosis treatment.
Sembulingam Tamilzhalagan   +17 more
doaj   +1 more source

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