Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang+4 more
core +1 more source
The reaction of Co(NO3)2·3H2O with pyridine-2,6-dicarboxylic acid and 3,5-dimethyl-1H-pyrazole in a 1:1:3 molar ratio affords the title complex, [Co(C7H3NO4)(C5H8N2)3]·H2O.
Kun-Hua Lin+3 more
doaj +1 more source
Synthesis and in Vitro Antimicrobial Activity of Some Pyrazolyl-1-carboxamide Derivatives
A series of 3,5-disubstituted pyrazole-1-carboxamides were obtained by treatment of chalcones with semicarbazide hydrochloride in dioxane containing sodium acetate/acetic acid as a buffer solution.
Essam Mohamed Sharshira+1 more
doaj +1 more source
Design, synthesis, in silico toxicity prediction, molecular docking, and evaluation of novel pyrazole derivatives as potential antiproliferative agents [PDF]
A new series of pyrazole derivatives were designed by docking into vascular endothelial growth factor receptor-2 (VEGFR-2) kinase active site. The designed compounds were synthesized and evaluated for in vitro antiproliferative activity against HT-29 ...
Chandra, Narendra Sharath JN+4 more
core +1 more source
THE REACTIONS OF THE FORMAMIDINES. IX. THE SYNTHESIS OF 5-PHENYL-4-PYRAZOLE CARBOXYLIC ACID. [PDF]
F. B. Dains, Wang Long
openalex +1 more source
Synthesis of an arginine mimic for an antifungal octapeptide library : this thesis is presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University, Palmerston North, New Zealand [PDF]
A family of bioactive antifungal octapeptides has been established¹⁻³. The template for this library is based on peptides composed of two predefined amino acids, three arginines, and three unknown components. The arginine contains a guanidino group (pKa =
Sun, Hao
core
Interfacial Photoelectrochemistry in Organic Synthesis
Photoelectrodes have traditionally enjoyed widespread attention as heterogeneous catalysts for the activation of water and CO2 in energy research, while photoelectrochemistry with homogeneous molecular catalysts dominates the activations of more complex molecules in organic synthesis.
Gabriel Chan+4 more
wiley +1 more source
In the present paper, pyrazole and pyrazoline derivatives of β-ionone were synthesized. The protocol involved intramolecular oxidative C–H amination of hydrazone to yield corresponding pyrazole in moderate to good yields.
Monika Sihag+10 more
doaj +1 more source
3-Methyl-5-phenyl-1-(3-phenylisoquinolin-1-yl)-1H-pyrazole
The title compound, C25H19N3, is composed of an aryl-substituted pyrazole ring connected to an aryl-substituted isoquinoline ring system with a dihedral angle of 52.7 (1)° between the pyrazole ring and the isoquinoline ring system. The
F. Nawaz Khan+4 more
doaj +1 more source