Results 141 to 150 of about 64,409 (320)

Postsynthetic Modifications of Amide‐Enaminone‐Based [2]Rotaxanes for the Stereocontrolled Synthesis of Functionalized β‐Lactams

ChemistryEurope, EarlyView.
Novel amido‐enaminone threads efficiently template the formation of hydrogen‐bonded [2]rotaxanes and enable diverse postsynthetic modifications. Benzyl groups promote diastereoselective cyclizations to interlocked lactams while the enaminone motif allows stopper exchange while preserving the mechanical bond.
Syed S. Razi, Isabel M. Perez‐Artigao, Mateo Alajarin, Alberto Martinez‐Cuezva, Jose Berna   +4 more
wiley   +1 more source

The Azidofunctionalization of Alkenes

ChemistryEurope, EarlyView.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Cationic Phosphino Beryllium Scorpionates and their Reactivity as Lewis Acid–Base Pairs

ChemistryEurope, EarlyView.
Monocationic tris(pyrazolyl)borate beryllium phosphine complexes are synthesized and characterized. These compounds readily react with substrates like CO2, SO2, H2, O2, S8, and Se8. Therefore, the nature of the BeP bond is also analyzed computationally. Herein, the article describes a facile and modular access to cationic beryllium phosphine complexes
Chantsalmaa Berthold, Deniz F. Bekiş, Jan Moritz, Gilles Stebens, Burkhard Butschke, Magnus R. Buchner   +5 more
wiley   +1 more source

Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper‐Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group

ChemistryEurope, EarlyView.
Copper‐mediated transient C─H sulfanylation of benzylamines with sulfenamides enables rapid access to thioethers, cyclic sulfilimines, and sulfoximines. Mechanistic investigations using 1H NMR and electron paramagnetic resonance spectroscopy reveal an unprecedented thermally induced homolytic cleavage of the sulfenamide N─S bond, slowly releasing the ...
Tsz‐Kan Ma, Peerawat Saejong, King‐Long Or, Callum S. Begg, James A. Bull   +4 more
wiley   +1 more source

Exploring the Potential Biological Activities of Pyrazole-Based Schiff Bases as Anti-Diabetic, Anti-Alzheimer’s, Anti-Inflammatory, and Cytotoxic Agents: In Vitro Studies with Computational Predictions

Pharmaceuticals
In this innovative research, we aim to reveal pyrazole-based Schiff bases as new multi-target agents. In this context, we re-synthesized three sets of pyrazole-based Schiff bases, 5a–f, 6a–f, and 7a–f, to evaluate their biological applications.
Ahmed M. Naglah, Abdulrahman A. Almehizia, Asma S. Al-Wasidi, Amirah Senaitan Alharbi, Mohammed H. Alqarni, Ashraf S. Hassan, Wael M. Aboulthana   +6 more
doaj   +1 more source

Synthetic studies of hydrazine and guanidine: derivatives of 5-pyrazoles [PDF]

, 1968
J. Zauhar, Benoit F. Ladouceur
openalex   +1 more source

Metal–Ligand Cooperation of Ir(III) Catalysts Bearing a β‐Protic Pyrazole Chelate in Carboxylative Cyclization of Propargylic Amine with CO2

Chemistry – A European Journal, EarlyView.
Proton‐responsive C–N chelating Cp*Ir complexes derived from 3,5‐diphenylpyrazole catalyze the carboxylative cyclization of propargylic amines with CO2. The cyclic urethane product is smoothly released via protonolysis of the alkenyl‐Ir species with the aid of the β‐protic NH unit on pyrazole.
Yoshihito Kayaki, Yuto Tsuda, Shigeki Kuwata   +2 more
wiley   +1 more source

Pyrazoles V: Di‐(1,3,5‐trimethyl‐4‐pyrazorylmethyl) ether, a product of the “chloromethylation” of 1,3,5‐trimethylpyrazole [PDF]

, 1968
C. Wijnberger, Clarisse L. Habraken
openalex   +1 more source

Synthesis of some isoxazoline, isoxazole and pyrazole carboxylic acids as the precursors of new 1,2-diacyl-1-alkylhydrazines [PDF]

, 2013
A number of isoxazoline, isoxazole and pyrazole carboxylic acids or their esters has been synthesized via the 1,3-dipolar cycloaddition of corresponding nitrile oxides or diazomethane to unsaturated dipolarophiles.
Antonevich, I. P., Katok, Ya. M.
core  

Oxidant‐Free Amidation of Aldehydes Enabled by Electrophotocatalysis

Chemistry – A European Journal, EarlyView.
An electrophotocatalytic method for C(sp2)–N bond formation via radical‐polar crossover (RPC)‐HAT catalysis is presented. The mild operating conditions enable functionalization of a wide range of compounds, with electricity as the sole oxidant. Abstract Electrophotocatalysis (EPC) is emerging as a powerful tool in organic synthesis, offering unique ...
Dimitris I. Ioannou, Elena Bombonato, Jiri Sanramat, Joost N. H. Reek, Timothy Noël   +4 more
wiley   +1 more source