Results 171 to 180 of about 64,409 (320)
Monometallic iron(II) and cobalt(II) complexes derived from potential hemilabile heterocyclic (pyrazolyl)imine catalyze ethylene oligomerization reactions upon activation with either EtAlCl2 or MAO to give predominantly butenes and hexenes. The catalytic activities are largely controlled by the complex structure and stabilization from the coordinated ...
Francis K. Migwi+3 more
wiley +1 more source
Targeting Ubiquitin-Specific Protease 7 with Novel 5-Amino-Pyrazole Inhibitors: Design, Synthesis, and Biological Evaluation. [PDF]
Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Lusardi M+9 more
europepmc +2 more sources
Variable coordination of peroxide: The reaction of the Cu(I) complex‐based on the BPMPD ligand with O2 at low temperatures initially led to a μ‐1,2 peroxo species (Cu2O2). By addition of an acid (lutidinium triflate), this species can be reversibly converted into a μ‐1,1‐hydroperoxo complex, which is monitored using UV/Vis spectroscopy and X‐ray ...
Alexander Stüber+10 more
wiley +1 more source
Design, Synthesis, and Molecular Docking Studies of Novel Pyrazoline-Thiazoles as Cholinesterase Dual-Target Inhibitors for the Treatment of Alzheimer's Disease. [PDF]
Kaya B+9 more
europepmc +1 more source
DMAPO/Boc2O‐Mediated One‐Pot Direct N‐Acylation of Sulfoximines with Carboxylic Acids
The one‐pot direct N‐acylation of NH sulsoximines with carboxylic acids is described. The method can be performed under mild low‐temperature reaction conditions and exhibits a wide substrate scope (> 60 examples). The present method is operationally simple, scalable, and practical; thus, it can find wide applications in both academic and industrial ...
Atsushi Umehara+2 more
wiley +1 more source
Comprehensive DFT study of 3-(2-furyl)-1 H-pyrazole-5-carboxylic acid: structural, spectroscopic, and electronic properties with optoelectronic implications. [PDF]
Yılmaz M.
europepmc +1 more source
Cross‐Coupling Reactions in Aqueous Micellar Media
Aqueous micellar media have emerged as sustainable alternatives to organic solvents for small‐molecule synthesis. This Review discusses the evolution of surfactants for synthesis, their application to cross‐coupling reactions, the benefits for reactivity and sustainability, and the remaining challenges in this rapidly growing field.
Alexander Uner, Liam T. Ball
wiley +1 more source
Synthesis of Novel Tetra-Substituted Pyrazole Derivatives Using Microwave Irradiation and Their Anti-Leukemic Activity Against Jurkat Cells. [PDF]
Machado FP+6 more
europepmc +1 more source