Results 51 to 60 of about 42,319 (209)

Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups. [PDF]

, 2020
In vivo compatible reactions have a broad range of possible applications in chemical biology and the pharmaceutical sciences. Here we report tetrazines that can be removed by exposure to isonitriles under very mild conditions.
Eckvahl, Hannah J, Franzini, Raphael M, Houk, KN, Parvez, Saba, Peterson, Randall T, Svatunek, Dennis, Tu, Julian, Xu, Minghao   +7 more
core  

Absorbate-Induced Piezochromism in a Porous Molecular Crystal [PDF]

, 2015
Atmospherically stable porous frameworks and materials are interesting for heterogeneous solid–gas applications. One motivation is the direct and selective uptake of pollutant/hazardous gases, where the material produces a measurable response in the ...
Butler, KT, Chen, T-H, Cruickshank, DL, Hendon, CH, Kaveevivitchai, W, Miljanic, OS, Popov, I, Walsh, A, Wilson, CC, Wittering, KE   +9 more
core   +3 more sources

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Oxidoperoxidomolybdenum(VI) complexes with acylpyrazolonate ligands: synthesis, structure and catalytic properties [PDF]

, 2018
Oxidoperoxido–molybdenum(VI) complexes containing acylpyrazolonate ligands were obtained by reaction of [Mo(O)(O)2(H2O)n] with the corresponding acylpyrazolone compounds HQR.
Begines, Emilio, Carrasco Carrasco, Carlos Jesús, Galindo del Pozo, Agustín, Marchetti, Fabio, Montilla Ramos, Francisco Javier, Pettinari, Claudio, Pettinari, Riccardo, Álvarez González, Eleuterio   +7 more
core   +1 more source

Characterization of the pattern of development of key compounds contributing to aroma quality of chicken meat and their metabolic markers

Animal Research and One Health, EarlyView.
The graphical abstract shows the principal results of this study. Eight major aroma‐contributing compounds (nonanal, octanal, dimethyl tetrasulfide, hexanal, 1‐octen‐3‐ol, (E)‐2‐nonenal, heptanal, and (E,E)‐2,4‐decadienal) were identified by electronic nose and GC‐O‐MS analysis, and their content increased with age.
Yanke Wang, Xiaojing Liu, Yongli Wang, Zhengxiao He, Guiping Zhao, Jie Wen, Huanxian Cui   +6 more
wiley   +1 more source

Preparation of multiblock copolymers via step-wise addition of l-lactide and trimethylene carbonate. [PDF]

, 2018
Poly(l-lactide) (PLA) is a bioderived and biodegradable polymer that has limited applications due to its hard and brittle nature. Incorporation of 1,3-trimethylene carbonate into PLA, in a block copolymer fashion, improves the mechanical properties ...
Abubekerov, Mark, Diaconescu, Paula L, Pei, Qibing, Swartz, Kevin R, Wei, Junnian, Xie, Zhixin   +5 more
core   +1 more source

Pharmacology and relevant drug interactions of metamizole

British Journal of Clinical Pharmacology, EarlyView.
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
David J. Brinkman, Linda C. Hendriksen, Irma M. Rigter, Markus W. Hollmann   +3 more
wiley   +1 more source

Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease [PDF]

, 2015
Background: Leukocyte cytosolic proteins (e.g., calprotectin) are emerging biomarkers for inflammatory bowel disease. Leukocyte aryl esterase activity has been commonly used for sensitive detection of leukocytes in human body fluids such as urine.
De Vos, Martine, Delanghe, Joris, Dumoulin, Els, Himpe, Jonas, Speeckaert, Marijn, Van Biervliet, Stephanie   +5 more
core   +2 more sources

A Polyproline type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein‐protein Interaction Implicated in Breast Cancer

ChemBioChem, Accepted Article.
Given the essential role of protein‐protein interactions (PPIs) in cellular signalling pathways their selective modulation is of great therapeutic interest. Mimicry of secondary structural protein elements has emerged as a promising strategy, with various scaffolds reproducing recognition surfaces of α‐helical and β‐strand/sheet proteins.
James Luccarelli, Philip C. Simister, Andrew D. Hamilton, Stephan M. Feller, Sam Thompson   +4 more
wiley   +1 more source

Synthesis of the isoquinoline alkaloid, crispine C [PDF]

, 2012
The first total synthesis of the isoquinoline alkaloid, crispine C is described in seven steps using a Henry reaction and the Pictet–Gams variant of the Bischler–Napieralski reaction to effect the key ...
Adele Blair, Ahluwalia, Allin, Amat, Andrew Sutherland, Bailey, Barker, Bernatowicz, Bernatowicz, Bernstein, Bischler, Bischoff, Blankespoor, Chiou, Coldham, Czarnocki, Dobrowsky, Dyke, Forrö, Gurram, Guénin, Hamilton, Hou, Kanemitsu, Kawai, King, Knolker, Louafi, Louise Stevenson, Luzzio, Meyer, Miyazaki, Ott, Pictet, Prudhommeaux, Reid, Saha, Szawkalo, Walker, Yasuhara, Yioti, Zaed, Zhang   +42 more
core   +1 more source