Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva +9 more
wiley +1 more source
Search for alkaloids on callus culture of Passiflora alata
Preliminary work on Passiflora alata leaves failed to detect harmane alkaloids using LC. The aim of this work was to investigate the production of harmane alkaloids through the cell culture of P. alata, inducing its precursor (L-tryptophan).
Michelli Wesz Machado +8 more
doaj +1 more source
Studies with Arylhydrazono-3-oxopropanals:A novel route to synthesis of substituted pyrazoles, oxoalkanonitrile and glyoxalonitrile containing sulfa drug moieties [PDF]
Coupling of enaminones 1 with diazonium salts gave thehydrazonopropanals 3a-h. Compound 3 react with ω-bromoacetophenone or α-chloroacetanilide to yield 5 and 8. These compounds were cyclized smoothly into 6 and 9 respectively.
Abdel Hafiz, I.S. +4 more
core
Synthesis of di(Imdazolium) and di(Pyrazolium) Salts as Precursors for N-heterocyclic Dicarbene Complexes [PDF]
Alpha,omega-bis(pyrazol-1-yl)alkanes and alpha,omega-bis(imidazol-1-yl)alkanes with spacers consisting of four to ten methylene groups have been prepared from pyrazole, 3,5-dimethylpyrazole or imidazole and corresponding dibromoalkanes in a superbasic ...
Tatiana V. Goncharova +12 more
core +1 more source
Pyrazole-Curcumin Suppresses Cardiomyocyte Hypertrophy by Disrupting the CDK9/CyclinT1 Complex [PDF]
Masafumi Funamoto +13 more
openalex +1 more source
Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley +1 more source
Novel fluorescent pyrazole-containing boron (III) complexes were synthesized employing a one-pot three-component reaction of 3-hydroxy-1-phenyl-1H-pyrazole-4-carbaldehyde, 2-aminobenzenecarboxylic acids, and boronic acids.
Viktorija Savickienė +4 more
doaj +1 more source
The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core +1 more source
Platinum group pincer complexes are highly efficient catalysts. Additionally, their high activity enables challenging transformations with low catalyst loading. Herein, we summarize the most relevant advances of catalysis involving platinum group pincer complexes. The use of pincer complexes based on platinum group metals is undoubtedly one of the most
Juan S. Serrano‐García +4 more
wiley +1 more source
New Pyrazolyl Thioureas Active against the Staphylococcus Genus
To meet the urgent need for new antibacterial molecules, a small library of pyrazolyl thioureas (PTUs) was designed, synthesized and tested against difficult-to-treat human pathogens.
Anna Maria Schito +6 more
doaj +1 more source

