Results 41 to 50 of about 4,108 (208)

Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains

open access: yesBeilstein Journal of Organic Chemistry, 2013
Starting from easily accessible gem-difluoropropargylic derivatives, a DBU-mediated isomerisation affords enones in fair yields with a gem-difluoroalkyl chain.
Assaad Nasr El Dine   +8 more
doaj   +1 more source

Investigation of Pyrazoline-Based Aromatic Sulfamates as Carbonic Anhydrase Isoforms I, II, IX, and XII Inhibitors

open access: yesMedical Sciences Forum, 2022
Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase, hCA I, II, IX, and XII.
Davide Moi
doaj   +1 more source

Reactivity of 4-tert-Butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with Hydrazines

open access: yesMolecules, 2006
The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described.
Manuel Medarde   +4 more
doaj   +1 more source

Komplexchemie perhalogenierter Cyclopentadiene und Alkine, VII [PDF]

open access: yes, 1990
Coordination Chemistry of Perhalogenated Cyclopentadienes and Alkynes, VII1). - Synthesis of Several Tetrachlorometalloles of Cobalt, Rhodium, and Iridium; Structure of a Iridacyclopentadiene Derivative The reaction of dichloroethyne with CpCo(PPh3)2 ...
Clarke   +15 more
core   +2 more sources

Synthesis and Crystal Structures of 4,5-Dihydroimidazo[1,5-b]pyrazol-6-ones

open access: yesSynOpen, 2020
The synthesis of previously unattainable 2,5-disubstituted 4,5-dihydroimidazo[1,5-b]pyrazol-6-ones has been developed. Electrochemical reductions of readily available 2,2,2-trichloroethylideneacetophenones were followed by reaction with hydrazine ...
Antonio Guirado   +6 more
doaj   +1 more source

Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow

open access: yesSynOpen, 2023
Pyrazolines and their pyrazole congeners are important heterocyclic building blocks with numerous applications in the fine chemical industries. However, traditional routes towards these entities are based on multistep syntheses generating substantial ...
Adam Burke   +3 more
doaj   +1 more source

Mesoionische N‐Heterocyclische Olefine, Imine, Thione, Phosphinidene und ihre Anwendung in der Katalyse

open access: yesAngewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Dieser Mini‐Review behandelt die neuesten Fortschritte bei der Synthese, Reaktivität und metallfreien katalytischen Verwendung von mesoionischen N‐heterocyclischen Olefinen (mNHOs), Iminen (mNHIs), Thionen (mNHTs) und Phosphinidenen (mNHPs). Kurzzusammenfassung Übergangsmetallverbindungen sind allgemein für ihre Fähigkeit bekannt, kleine Moleküle zu ...
Subir Maji   +3 more
wiley   +1 more source

Synthesis and tautomerism of spiro-pyrazolines [PDF]

open access: yesTetrahedron Letters, 2014
An experimental study on the synthesis, tautomerism and acid promoted structural changes of spiro-pyrazolines is described. The target was achieved through a [3+2]-dipolar cycloaddition of an alkene with nitrile imines generated in situ and was isolated in high yield.
Sureshbabu, Dadiboyena   +2 more
openaire   +2 more sources

Matrix Metalloproteinase Inhibition in Melanoma

open access: yesExperimental Dermatology, Volume 35, Issue 1, January 2026.
ABSTRACT Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix (ECM) and are found to participate in all stages of tumour progression including modifying signalling pathways, regulating cytokines and promoting tumour growth, particularly by inducing angiogenesis and facilitating cancer spread.
Ellie Zhang   +2 more
wiley   +1 more source

Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal   +6 more
wiley   +1 more source

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