Results 51 to 60 of about 4,108 (208)

SOCl2 catalyzed cyclization of chalcones: Synthesis and spectral studies of some bio-potent 1H pyrazoles

open access: yesBulletin of the Chemical Society of Ethiopia, 2014
Some aryl-aryl 1H pyrazoles have been synthesised by cyclization of aryl chalcones and hydrazine hydrate in the presence of SOCl2. The yields of the pyrazoles are more than 85%.
K. Ranganathan   +5 more
doaj   +1 more source

Recent advances in the synthesis and application of fluorescent α-amino acids [PDF]

open access: yes, 2016
Fluorescence spectroscopy has become a powerful technique for probing a range of complex biological processes including enzyme mechanisms and protein-protein interactions. While the application of this technique uses a number of strategies, many of these
Harkiss, Alexander, Sutherland, Andrew
core   +1 more source

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

open access: yes, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel   +6 more
core   +1 more source

Synthetic Strategies to Access Fluorinated Azoles

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber   +4 more
wiley   +1 more source

Chemical Coordination Induced Fullerene Dimers on Hot Pt(111)

open access: yesAngewandte Chemie, Volume 137, Issue 33, August 11, 2025.
The thermal evolution of C60${\rm C}_{60}$ islands on Pt(111) includes the transition from segregated fullerene islands to dimers and the subsequent growth of graphene quantum dots. After annealing at 800K$800 \,\mathrm{K}$, the coordination of C60${\rm C}_{60}$ molecules promotes structural transformations toward separated dimers, with potential for ...
Zhao Liu   +4 more
wiley   +2 more sources

Antinociceptive effect of novel pyrazolines in mice

open access: yesBrazilian Journal of Medical and Biological Research, 2004
The antinociceptive effect of six novel synthetic pyrazolines (3-ethoxymethyl-5-ethoxycarbonyl-1H-pyrazole (Pz 1) and its corresponding 1-substituted methyl (Pz 2) and phenyl (Pz 3) analogues, and 3-(1-ethoxyethyl)-5-ethoxycarbonyl-1H-pyrazole (Pz 4) and
Z. Tabarelli   +10 more
doaj   +1 more source

2-пиразолины с 8-гидроксихинолиновым заместителем [PDF]

open access: yes, 2008
Осуществлен синтез 2-пиразолинов на основе халконов 8-гидроксихинолинового ряда и фенилгидразина, строение пиразолинов подтверждено данными элементного анализа, ИК. .1Н ЯМР и электронной спектроскопии.
Марруго Гонсалес, А.Х.   +2 more
core  

2-Pyrazoline derivatives in neuropharmacology [PDF]

open access: yes
A novel series of 1,3,5-trisubstituted-2-pyrazoline derivatives (PFC-1 to PFC-16) were synthesized in a three step reaction using conventional and microwave assisted green chemistry approach.
Paliwal, Sarvesh   +3 more
core   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

open access: yesChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Cytotoxic potential of novel N-formyl pyrazolines derived from vanillin [PDF]

open access: yesKragujevac Journal of Science
In the reaction of vanillin and acetone under Claisen-Schmidt conditions, dehydrozingerone, a very attractive biologically active compound, is obtained.
Muškinja Jovana M.   +6 more
doaj   +1 more source

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