Results 81 to 90 of about 4,108 (208)
SynOpen, 2018 A novel series of 3-(4-fluorophenyl)-4,5-dihydro-5-(3,4,5-trimethoxy/4-nitro phenyl)-N-(substituted-phenyl)pyrazole-1-carboxamide analogues 4a–n was synthesized in two steps from 4-fluoroacetophenone.
Mohamed J. Ahsan +8 more
doaj +1 more source
Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides [PDF]
, 2014 A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium.
Anbazhagan, S. +2 more
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European Journal of Inorganic Chemistry, Volume 28, Issue 22, August 20, 2025.Dinuclear (pyrazolyl)amine cobalt(II) complexes are synthesized and structurally characterized. Activation of these cobalt(II) complexes with EtAlCl2 cocatalyst affords highly active and selective ethylene dimerization catalysts. The steric parameters induced by the pyrazolyl substituents largely influence both the catalytic activity and selectivity of
Francis K. Migwi +2 more
wiley +1 more source
Asymmetric organocascades involving the formation of two C-heteroatom bonds from two distinct heteroatoms [PDF]
, 2012 International audienceIn the vast and expanding world of enantioselective organocascades, the ones in which two C-heteroatom bonds are created from two distinct heteroatoms are rare.
Bonne, Damien +3 more
core +3 more sources
Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives
Applied Sciences, 2013 A series of new 1,3-diaryl-5-(1-phenyl-3-methyl-5-chloropyrazol-4-yl)-4,5-dihydropyrazole derivatives have been synthesized under sonication conditions in ethanol or methanol/glacial acetic acid mixture (5/1 ratio) with two equivalents of hydrazines and ...
Manuel Nogueras +4 more
doaj +1 more source
Synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones [PDF]
, 2012 BACKGROUND: The currently available antifungal drugs suffer from toxicity, greatest potential drug interactions with other drugs, insufficient pharmacokinetics properties, and development of resistance.
Adile Ayati +3 more
core +1 more source
Molecules, 2018 The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole ring has been performed through a 1,3-dipolar cycloaddition reaction of N-thiocarbamoylpyrazoline and different hydrazonoyl halides or α-haloketones in the
Mastoura M. Edrees +5 more
doaj +1 more source
Metal-catalyzed cyclopropanation on the 8-oxabicyclo[3.2.1]oct-6-ene template [PDF]
, 2005 Cyclopropanations of an 8-oxabicyclo[3.2.1]octene substrate using diazocarbonyl compounds provided exo, exo-cyclopropanated products as the sole or major diastereomeric oxatricyclic products.
Chiu, P, Leung, SK
core +1 more source
Advanced Science, Volume 12, Issue 29, August 7, 2025.L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang +8 more
wiley +1 more source
Sintesis Analog 4-bromo Pirazolin dari Kalkon Inti Naftalen dengan Katalis Asam dan Uji Aktivitas Nya sebagai Antibakteri [PDF]
, 2014 Pyrazolines have been reported to possess various biological activities such as antimicrobial, antidepressant, antidiabetic, anti-inflammatory, antipyretic, anticancer, and anticonvulsant activity. In this research, a halogenated pirazoline 5-(4-
Hariyanti, D. (Desy) +2 more
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