Results 121 to 130 of about 5,326,384 (292)

Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors

International Journal of Cancer, EarlyView.
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan, Nicholas Woytowich, Tian Zhao, Kiera Nguyen, Emily Mahony, Julian J. Lum, Kyle D. Duncan   +6 more
wiley   +1 more source

Exploring pyridinium-based inhibitors of cholinesterases: A review of synthesis, efficacy, and structural insights

European Journal of Medicinal Chemistry Reports
Pyridinium-based compounds have emerged as promising multifunctional agents for Alzheimer's disease therapy, demonstrating remarkable dual inhibition of acetylcholinesterase and butyrylcholinesterase.
Efraín Polo-Cuadrado, Cristian Rojas-Peña, Karen Acosta-Quiroga, Lorena Camargo-Ayala, Yeray A. Rodríguez-Núñez, Edison Osorio, Jhon J. López, Rhonny Brid-Cuadrado, Margarita Gutierrez   +8 more
doaj   +1 more source

Ionic liquids: structure–toxicity relationships, predictive toxicology, and sustainable design

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Ionic liquids (ILs) have often been described as green alternatives to conventional solvents because of their negligible vapor pressure and highly tunable properties. However, low volatility does not necessarily translate into environmental safety, as their biological and ecological effects are strongly influenced by molecular structure.
Letícia Zanchet, Letícia Guerreiro da Trindade, Monize Bürck, Gabriela Rosa dos Santos, Matheus Klein, Aryel Heitor Ferreira   +5 more
wiley   +1 more source

Gold(I)‐Catalyzed Annulation of Pyridines Containing Alkyne: Synthesis of N‐Alkenyl Pyridonyl Azides via Rearrangement

Journal of Heterocyclic Chemistry, EarlyView.
One‐pot gold(I)‐catalysts synthesis was developed in order to prepare N‐alkenyl 2‐pyridonyl azides. This method provides a series of N‐alkenyl 2‐pyridonyl azides in moderate to excellent yields (up to 94%). ABSTRACT A novel strategy, involving the preparation of gold‐catalyzed cyclization salts and the rearrangement of these salts in the presence of ...
Ali Osman Karatavuk
wiley   +1 more source

Ferroelectricity of Inclusion Compounds of Thiourea with Pyridinium Iodide and Nitrate

, 2009
International audienceThe character of phase transitions in the inclusion compounds of thiourea with pyridinium iodide and nitrate has been analyzed, and a model of ferroelectricity of these compounds has been proposed.
Pajzderska, Aleksandra, Collet, Eric, Wąsicki, Jan, Czarnecki, Piotr   +3 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Reactivation of phosphorylated acetocholinesterases by pyridinium aldoximes and related compounds [PDF]

Biochemical Journal, 1960
F, HOBBIGER, M, PITMAN, P W, SADLER
openaire   +2 more sources

Cross‐Scale Engineering of Single‐Atom Catalysts from Local Planar Coordination to Spatial Architectures

Small, EarlyView.
This Review presents a cross‐scale framework for single‐atom catalysts, spanning in‐plane and out‐of‐plane coordination; primary coordination, secondary‐sphere interactions, through‐space microenvironments and support interfaces; individual sites and macroscopic architectures; and static design and directed dynamic reconstruction.
Dazhi Yao, Siheng Yang, Shuhao Wang, Bernt Johannessen, Cheng Tang   +4 more
wiley   +1 more source

Solid-phase synthesis and cytotoxic evaluation of novel pyridinium bromides

Scientific Reports
A series of amide-based mono and dimeric pyridinium bromides were synthesized using conventional and microwave-assisted solvent-free methods. The quaternization reactions of m-xylene dibromide and 4-nitrobenzylbromide with amide-based substituted ...
Sadaiyan Govindaraj, Kilivelu Ganesan, Perumal Elumalai, Rajanathadurai Jeevitha, Jospin Sindya, Subramani Annadurai, Shiek S. S. J. Ahmed, Mudassar Shahid   +7 more
doaj   +1 more source

Super‐Electron‐Donor Polymers: From Monomer Design to Redox Functionality

Small, EarlyView.
2,2'‐Bipyridinylidenes are known for their “super‐electron‐donor” properties and have therefore been used beyond the field of organic synthesis. Their two‐electron redox process at a low potential of 1.8 V vs. Li/Li+ makes them attractive negative p‐type electrode‐active materials.
Luisa Rzesny, Aswadh Shyma Sajeevan, Caroline Schmidt, Johannes Lahr, Christoph Lorenz, Mathias Hermann, Nicolas Dupré, Stéven Renault, Philippe Poizot, Birgit Esser   +9 more
wiley   +1 more source