Marine Drugs, 2023 Four new compounds, including two ascochlorin-type meroterpenoids acremocholrins A (1) and B (2), one pyridone alkaloid acremopyridone A (7), and one cyclopentenone derivative acremoketene A (12), together with eight known compounds (3–6 and 8–11), were ...
Yan Zhang +7 more
doaj +1 more source
Nicotinamide (Vitamin B3) Deficiency in Follicular Fluid of Patients With Ovarian Ageing
Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT Nicotinamide is an essential precursor of NAD involved in energy metabolism. A decline in NAD levels across tissues during ageing is well‐documented, and NAD metabolism has been implicated in ovarian ageing. We investigated the relationship between ovarian ageing and the levels of nicotinamide (NAM) and its metabolite 1‐methylnicotinamide (MNA)
Cinzia Bocca +5 more
wiley +1 more source
Synthesis and chemical properties of 3-acyl- and 3-carbethoxy-4-pyrones [PDF]
, 2013 Реакция 1-арил-2-диметиламинометиленбутан-1,3-дионов с диэтиоксалатом в присутствии гидрида натрия в ТГФ приводит к образованию этил 5-ароил-4-оксо-4Н-пиран-2- карбоксилатам, из которых 4-оксо-6-арил-4Н-пиран-2-карбоновые кислота (6- арилкомановая ...
Obydennov, D. L. +1 more
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A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria [PDF]
, 2017 A marine-derived Stilbella fimetaria fungal strain was screened for new bioactive compounds based on two different approaches: (i) bio-guided approach using cytotoxicity and antimicrobial bioassays; and (ii) dereplication based approach using liquid ...
Andersen, Birgitte +10 more
core +1 more source
Synthesis, structure and solvatochromic properties of 3-cyano-4,6-diphenyl-5-(3- and 4-substituted phenylazo)-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2010 A series of some new pyridone arylazo dyes was synthesized from the corresponding diazonium salts and 3-cyano-4,6-diphenyl-2-pyridone using the classical reaction for the synthesis of the azo compounds.
NINA TODOROVIĆ +5 more
doaj
Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance
The FASEB Journal, Volume 40, Issue 3, 15 February 2026.Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon +6 more
wiley +1 more source
[2,2′-Bipyridin]-6(1H)-one, a Truly Cooperating Ligand in the Palladium-Mediated C–H Activation Step: Experimental Evidence in the Direct C-3 Arylation of Pyridine [PDF]
, 2018 Producción CientíficaThe ligand [2,2′-bipyridin]-6(1H)-one (bipy-6-OH) has a strong accelerating effect on the Pd- catalyzed direct arylation of pyridine or arenes.
Albéniz Jiménez, Ana Carmen +2 more
core +4 more sources
Advanced Energy and Sustainability Research, Volume 7, Issue 2, February 2026.This study introduces two new fluorine‐free ionic liquids (ILs) produced by coupling biomass‐derived heterocyclic anions, i.e., THP and 3‐FuA, with P4444 cation. Both the ILs display enhanced capacitance with increasing temperature, underscoring their potential as fluorine‐free electrolytes for supercapacitors.
Gaurav Tatrari +4 more
wiley +1 more source
Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma [PDF]
, 2013 Recurrence of Head and Neck Squamous Cell Carcinoma (HNSCC) is common; thus, it is essential to improve the effectiveness and reduce toxicity of current treatments.
Jaseja, Reshma, Jaseja, Reshma
core
Antimalarial 4(1H)-pyridones bind to the Qisite of cytochromebc1 [PDF]
, 2015 Cytochrome bc1 is a proven drug target in the prevention and treatment of malaria. The rise in drug-resistant strains of Plasmodium falciparum, the organism responsible for malaria, has generated a global effort in designing new classes of drugs. Much of
Antonyuk, SV +10 more
core +1 more source