Results 91 to 100 of about 12,719 (269)
Synthesis of 4-Pyridone-3-sulfate and an improved synthesis of 3-Hydroxy-4-Pyridone [PDF]
Chemistry Central Journal, 2009 An improved synthesis of 3-hydroxy-4-pyridone via an Elbs oxidation of 4-pyridone and isolation of 4-pyridone-3-sulfate is described.
openaire +4 more sources
Designing Enzymatic Reactivity with an Expanded Palette
ChemBioChem, Volume 26, Issue 11, June 3, 2025.Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley +1 more source
Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
Molecules, 2005 Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle +3 more
doaj +1 more source
Organometallic catalysis for applications in radical chemistry and asymmetric synthesis [PDF]
, 2014 Two organometallic catalysis studies are presented. The first one deals with the development of a new catalytic agent based on the mixture of a hydride and an iron salt to trigger efficient radical cyclization processes.
Ateywiohrera +17 more
core +2 more sources
Liver International, Volume 45, Issue 6, June 2025.ABSTRACT Background Advanced liver fibrosis (ALF) predicts an adverse prognosis in chronic liver disease. In addition to etiological treatment, a new approach to stop or reverse residual fibrosis is desirable. Objective To assess the efficacy and safety of prolonged‐release pirfenidone (PR‐PFD) versus placebo in compensated cirrhosis.
Linda E. Muñoz‐Espinosa +17 more
wiley +1 more source
Synthesis of a Pyridone ALkaloid, Cerpegin.
Chemical and Pharmaceutical Bulletin, 1995 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Takahiko Arase, Keizo Matsuo
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Phenacylation of 6-Methyl-Beta-Nitropyridin-2-Ones and Further Heterocyclization of Products
Molecules, 2020 Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated.
Eugene V. Babaev, Victor B. Rybakov
doaj +1 more source
Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones [PDF]
, 2008 trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro ...
Habuš, Ivan +3 more
core +1 more source
Activation of Small Molecules by Readily Accessible Alkylborane‐Based Frustrated Lewis Pairs
European Journal of Inorganic Chemistry, Volume 28, Issue 15, May 28, 2025.Simple alkylborane‐based frustrated Lewis pairs (FLPs) are demonstrated to activate hydrogen, ammonia, the NH bond of secondary amines, and the CH bonds of terminal alkynes, highlighting the potential of readily accessible FLPs for small‐molecule activation.
Arthur Averdunk +3 more
wiley +1 more source
Scientific Reports, 2017 We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction.
Gang Cheng +5 more
doaj +1 more source