Results 111 to 120 of about 9,290 (210)

Pharmacological treatments for Friedreich ataxia [PDF]

, 2016
BACKGROUND: Friedreich ataxia is a rare inherited autosomal recessive neurological disorder, characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties.
Brassington, R, Fahey, M, Kearney, M, Orrell, RW, Pandolfo, M   +4 more
core  

Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug [PDF]

, 2017
Plasmodium parasites undergo a clinically silent and obligatory developmental phase in the host's liver cells before they are able to infect erythrocytes and cause malaria symptoms.
Buchholz, Kathrin, da Cruz, Filipa P., Gamo, Francisco-Javier, Hannus, Michael, Lafuente-Monasterio, Maria J., Marti, Matthias, Martin, Cécilie, Moreira, Rui, Mota, Maria M., Prudêncio, Miguel, Rodrigues, Tiago, Sönnichsen, Birte   +11 more
core  

Antimicrobial and antioxidative activities of 1-adamantylthio derivatives of 3-substituted pyridines [PDF]

, 2008
Diverse biological activities of sulfur containing pyridines were reported. To investigate for new lead compounds, thus, 1-adamantylthiopyridines bearing 3-substituents (OEt, OAc, NAc2, Br and OH) were prepared and evaluated for antimicrobial and ...
Isarankura-Na-Ayudhya, Chartchalerm, Prachayasittikul, Supaluk, Prachayasittikul, Virapong, Ruchirawat, Somsak, Suksrichavalit, Thummaruk   +4 more
core  

Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones [PDF]

, 2016
Gallagher, Timothy, Honraedt, Aurelien
core   +1 more source

Tautomeric Equilibria Studies by Mass Spectrometry [PDF]

, 2008
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro, Jorge J. Furlong, Mercedes M. Schiavonni, Patricia E. Allegretti   +3 more
core   +1 more source

Reaction of acyclic enaminones with methoxymethylene meldrum's acid: synthetic and structural implications

Journal of the Brazilian Chemical Society, 2003
The reaction of acyclic enaminones with methoxymethylene Meldrum's acid afforded N-adduct and/or C-adduct of enaminones in moderate to good yields. The regiochemistry of this reaction depends on the N-amino substituent of the enaminone. The C-adduct is a
Cunha Silvio, Silva Viviane C. da, Napolitano Hamilton B., Lariucci Carlito, Vencato Ivo   +4 more
doaj  

GABAA receptor diversity and pharmacology [PDF]

, 2018
Because of its control of spike-timing and oscillatory network activity, γ-aminobutyric acid (GABA)-ergic inhibition is a key element in the central regulation of somatic and mental functions.
Möhler, H.
core  

Competitive cyclization of ethyl trifluoroacetoacetate and methyl ketones with 1,3-diamino-2-propanol into hydrogenated oxazolo- and pyrimido-condensed pyridones. [PDF]

Beilstein J Org Chem
Kushch SO, Goryaeva MV, Burgart YV, Ezhikova MA, Kodess MI, Slepukhin PA, Volobueva AS, Zarubaev VV, Saloutin VI.   +8 more
europepmc   +1 more source

Formal [1 + 2 + 3] Annulation of Anilines and CF₃‑Containing Ynones via 6π-Electrocyclization. [PDF]

Precis Chem
Feng L, Ni SF, Lai Y, Zhang X, Lu ZX, Xiong HY, Zhang G, Wang T.   +7 more
europepmc   +1 more source

Multicomponent synthesis of pyrano-pyrazolo-pyridones by a bimetallic cobalt-cadmium magnetic catalyst. [PDF]

Sci Rep
Kamali M, Mobaraki A, Shirpak Z.
europepmc   +1 more source