Results 11 to 20 of about 20,092 (323)
mBio, 2021 Diverse 2-pyridone alkaloids have been identified with an array of biological and pharmaceutical activities, including the development of drugs. However, the biosynthetic regulation and chemical ecology of 2-pyridones remain largely elusive.
Bo Chen +4 more
doaj +2 more sources
Two New Antibiotic Pyridones Produced by a Marine Fungus, Trichoderma sp. Strain MF106 [PDF]
Marine Drugs, 2014 Two unusual pyridones, trichodin A (1) and trichodin B (2), together with the known compound, pyridoxatin (3), were extracted from mycelia and culture broth of the marine fungus, Trichoderma sp. strain MF106 isolated from the Greenland Seas.
Bin Wu +4 more
doaj +3 more sources
Photochemical Cycloadditions to 5,6-Dihydro-4-pyridones [PDF]
CHIMIA, 1987 5,6-Dihydro-4-pyridones (3a-3c) undergo photochemical [2 + 2]-cycloaddition with olefins activated by an electron withdrawing group. Alkyl substituted double bonds could only be brought to react in the intramolecular cases 3d and 3e.
Philippe Guerry, Reinhard Neier
doaj +3 more sources
Synthesis and Characterization of New 3-Cyano-2-Pyridone Derivatives as Fluorescent Scaffolds
Chemistry Proceedings, 2023 2-pyridones are among the most widely used nitrogen-containing heterocyclic derivatives in various fields due to their structural properties and biological and therapeutic activities.
Asmaa Kebaili +5 more
doaj +1 more source
mBio, 2023 Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by binding and ...
Hasan Tükenmez +10 more
doaj +1 more source
Organic Letters, 2021 A rhodium-catalyzed C4-selective C-H alkenylation of 3-carboxy-2-pyridones with styrenes has been developed. The carboxylic group at the C3 position works as the traceless directing group, and the corresponding C4-alkenylated 2-pyridones are obtained ...
Sunit Hazra, K. Hirano, M. Miura
semanticscholar +1 more source
Acta Crystallographica Section E Structure Reports Online, 2011 The crystal structure of the title compound, C(6)H(7)NO, is stabilized by inter-molecular N-H⋯O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C-H⋯O hydrogen bonds.
Shu-Lin Mao, Pan Meiling, Luo Yanghui
openaire +4 more sources
Molecules, 2023 This work describes the synthesis of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones, their tautomerism, and reactivity towards binucleophiles. These molecules are novel and convenient building-blocks for the direct construction of biologically
Viktoria V. Viktorova +3 more
doaj +1 more source
Reactions of 2-methylchromones with cyanoacetamides and ethyl cyanoacetate. synthesis of 6-(2-hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3- carbonitriles and 7-hydroxy-6-imino-9-methyl-6h-benzo[c]chromene-8-carbonitriles [PDF]
, 2005 Although 2-methylchromones react with cyanoacetamide and N-methyl cyanoacetamide in the presence of sodium ethoxide in refluxing ethanol to produce 6-(2-hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitriles, their reactions with ethyl ...
Ito, Hiroharu +7 more
core +3 more sources
13C- and 1H-NMR substituent-induced chemical shifts in N(1)-(4-substituted phenyl)-3-cyano-4,6-dimethyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2008 The 13C- and 1H-NMR chemical shifts of thirteen N(1)-(4-substituted phenyl)-3-cyano-4,6-dimethyl-2-pyridones were measured in deuterated dimethyl sulfoxide (DMSO-d6).
Marinković Aleksandar D. +4 more
doaj +3 more sources