Structural and functional studies on human and Escherichia coli pyridoxal kinases
Pyridoxal kinase is an ATP dependent enzyme that phosphorylates pyridoxal, pyridoxine, and pyridoxamine forming their respective 5-phosphorylated esters.
BOSSA, Francesco +5 more
core
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang +15 more
wiley +1 more source
Potential Role of Vitamin B6 as an Antioxidant via Pyridoxal-5'-Phosphate-Dependent Metabolic Pathways and Subsequent Activation of Nrf2 Signaling. [PDF]
Kato N, Yang Y, Khedara A, Kumrungsee T.
europepmc +1 more source
Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen +5 more
wiley +1 more source
Allelic variation alters expression and antigen presentation of MR1 allomorphs. [PDF]
Nelson AG +16 more
europepmc +1 more source
Pediatric Wilson Disease in Sudan: A Rare Case, Sudan Conflict and Diagnostic Challenges
ABSTRACT Wilson disease is rarely reported among African children. Wilson disease is due to a mutation in ATP7B on an autosomal recessive pattern, which causes defective copper excretion and copper accumulation in tissues such as liver and brain.
Amjed Abdu Ali Mohammed +8 more
wiley +1 more source
Stress-induced enrichment of Pseudomonas sp. stimulates the adaptive response of Auxenochlorella pyrenoidosa and antibiotic-resistant proliferation. [PDF]
Liu Q, Jia J, Chen X, Wu C.
europepmc +1 more source
Bioenhancer‐Driven Modulation of Membrane Dynamics Improves B‐Vitamin Uptake in Caco‐2 Cells
Natural bioenhancers such as extracts from ginger, turmeric, black pepper, and spearmint increase the uptake of vitamins B1, B5, B6, and B7 in Caco‐2 cells. Micellized formulations further increase efficacy. These findings indicate that altered membrane fluidity contributes to enhanced cellular absorption, providing a new route to improve vitamin B ...
Verena Preinfalk +9 more
wiley +1 more source
Impact of various types of heat treatment on the content of selected B vitamin and their profile in goose breast meat. [PDF]
Goluch Z +4 more
europepmc +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source

