How Does Pyridoxamine Inhibit the Formation of Advanced Glycation End Products? The Role of Its Primary Antioxidant Activity [PDF]
Antioxidants, 2019 Pyridoxamine, one of the natural forms of vitamin B6, is known to be an effective inhibitor of the formation of advanced glycation end products (AGEs), which are closely related to various human diseases.
Rafael Ramis +7 more
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Haematologica, 2019 Adherent neutrophils on vascular endothelium positively contribute to cell-cell aggregation and vaso-occlusion in sickle cell disease. In the present study, we demonstrated that pyridoxamine, a derivative of vitamin B6, might be a therapeutic agent to ...
Jing Li +7 more
doaj +4 more sources
Significantly Elevated Levels of Plasma Nicotinamide, Pyridoxal, and Pyridoxamine Phosphate Levels in Obese Emirati Population: A Cross-Sectional Study [PDF]
Molecules, 2020 Water-soluble vitamins like B3 (nicotinamide), B6 (pyridoxine), and B9 (folic acid) are of utmost importance in human health and disease, as they are involved in numerous critical metabolic reactions. Not surprisingly, deficiencies of these vitamins have
Ghada Rashad Ibrahim +5 more
doaj +3 more sources
Pyridoxamine inhibits dopamine-induced α-synuclein oligomerization through scavenging neurotoxic dopamine quinone [PDF]
Scientific ReportsParkinson’s disease (PD) is a neurodegenerative disease characterized by loss of dopaminergic neurons causing reduced levels of dopamine (DA), and the presence of Lewy bodies, whose main component is fibrillar α-synuclein (α-Syn).
Seon Hwa Lee +4 more
doaj +4 more sources
Validation of the Vitamin B6 Profile (Pyridoxine, Pyridoxal, and Pyridoxamine) Analysis in Rice Consumed in Korea: Effects of Cooking and Variety [PDF]
FoodsRice, a widely consumed grain, contains various forms of vitamin B6, including pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM). However, limited information exists on their content and distribution in rice.
Minyoung Je, Hui Jin Lee, Jiyeon Chun
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Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy [PDF]
Journal of Diabetes Research, 2016 Objective. Diabetic nephropathy is a life-threatening complication in patients with long-standing diabetes. Hemodynamic, inflammatory, and metabolic factors are considered as developmental factors for diabetic nephropathy.
Tarek Kamal Abouzed +7 more
doaj +3 more sources
Antioxidants, 2021 The thermodynamic stability of 11 complexes of Cu(II) and 26 complexes of Fe(III) is studied, comprising the ligands pyridoxamine (PM), ascorbic acid (ASC), and a model Amadori compound (AMD).
Guillermo García-Díez +2 more
doaj +2 more sources
Conversion of pyridoxal to pyridoxamine with NH<sub>3</sub> and H<sub>2</sub> on nickel generates a protometabolic nitrogen shuttle under serpentinizing conditions. [PDF]
FEBS JSerpentinizing hydrothermal vents are likely sites for the origin of metabolism because they produce H2 as a source of electrons for CO2 reduction while depositing zero‐valent iron, cobalt, and nickel as catalysts for organic reactions.
Schlikker ML +7 more
europepmc +2 more sources
Molecular Metabolism, 2019 Objective: The impact of diabetes mellitus on the central nervous system is less widely studied than in the peripheral nervous system, but there is increasing evidence that it elevates the risk of developing cognitive deficits.
Sarah Kassab +12 more
doaj +2 more sources
Pyridoxamine Limits Cardiac Dysfunction in a Rat Model of Doxorubicin-Induced Cardiotoxicity
AntioxidantsThe use of doxorubicin (DOX) chemotherapy is restricted due to dose-dependent cardiotoxicity. Pyridoxamine (PM) is a vitamin B6 derivative with favorable effects on diverse cardiovascular diseases, suggesting a cardioprotective effect on DOX-induced ...
Sibren Haesen +15 more
doaj +2 more sources