The effect of aminoguanidine (AG) and pyridoxamine (PM) on ageing human cortical bone [PDF]
Bone & Joint Research, 2018 Objectives Advanced glycation end-products (AGEs) are a post-translational modification of collagen that form spontaneously in the skeletal matrix due to the presence of reducing sugars, such as glucose.
O. Abar, S. Dharmar, S. Tang
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Frontiers in Pharmacology, 2019 Neonatal epileptic encephalopathy (NEE), as a result of pyridoxine 5′-phosphate oxidase (PNPO) deficiency, is a rare neural disorder characterized by intractable seizures and usually leads to early infant death.
Po-Yuan Chen +5 more
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Case report: Hepatocellular carcinoma in a patient with Pyridoxamine 5-phosphate oxidase (PNPO) deficiency undergoing pyridoxal 5-phosphate (PLP) treatment [PDF]
Molecular Genetics and Metabolism ReportsPyridoxamine 5-phosphate oxidase (PNPO) deficiency is an autosomal recessive inborn error of metabolism that typically manifests as seizures resistant to conventional anticonvulsants, often presenting in the neonatal period to early infancy.
Jesse Zhen Cheng Lee +4 more
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Vitamin B6 form produced by Lactobacillus induces metabolic disorder and suppresses multi-pathogenic bacteria [PDF]
Communications BiologyVitamin B6 comprises six vitamers, pyridoxal, pyridoxine, pyridoxamine, pyridoxal 5′-phosphate (PLP), pyridoxine 5′-phosphate (PNP), and pyridoxamine 5′-phosphate (PMP), recognized for pleiotropic functions in mitigating oxidative stress and modulating ...
Ying Wu +9 more
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Plasma vitamin levels and pathway analysis in boys with autism spectrum disorders [PDF]
Scientific ReportsAbnormal feeding behaviors and inadequate nutrient intake of children with autism spectrum disorder (ASD) have been reported. This study aimed to examine the plasma vitamin status of boys with autism spectrum disorder (ASD) and to analyze the association
Lili Zhang +5 more
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Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice. [PDF]
PLoS ONE, 2016 Age-related increases in oxidant stress (OS) play a role in regulation of estrogen receptor (ER) expression in the kidneys. In this study, we establish that in vivo 17β-estradiol (E2) replacement can no longer upregulate glomerular ER expression by 21 ...
Simone Pereira-Simon +6 more
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Inhibition effect of pyridoxamine on lipid hydroperoxide-derived modifications to human serum albumin. [PDF]
PLoS ONE, 2018 Pyridoxamine (PM) is a promising drug candidate for treating various chronic conditions/diseases in which oxidative stress and carbonyl compounds are important factors affecting pathogenicity. These abilities of PM are mainly attributed to its inhibition
Seon Hwa Lee +2 more
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Scavenging methylglyoxal improves bone quality and defect healing in diabetic mice [PDF]
Bone ReportsHyperglycemia in diabetes leads to the formation of methylglyoxal (MG) and accumulation of advanced glycation end-products (AGEs). We previously reported that exogenous MG exposure deteriorated osteoblastic differentiation in vitro and diabetic mice ...
Toshifumi Hikichi +12 more
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Studies on Nickel(II)-Pyridoxamine-Imidazole Containing Mixed Ligand Complex Systems [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2004 The stability constants of species present in the systems Ni(II)-pyridoxamine(pym)(A) and Ni(II)-pyridoxamine(pym)(A)-imidazole containing ligands(B) [B = imidazole(him), benzimidazole(bim), histamine(hist) and L-histidine(his)] have been determined pH ...
M.A Neelakantan, M . Sivasankaran Nair
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Late-onset drug-resistant epilepsy in pyridoxamine 5′-phosphate oxidase deficiency: a case report [PDF]
Journal of Medical Case ReportsBackground Pyridoxamine 5′-phosphate oxidase deficiency is a rare inborn error of vitamin B6 metabolism that presents with drug-resistant epileptic seizures.
Erfan Naghavi +8 more
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