Results 11 to 20 of about 4,991,696 (204)

Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects [PDF]

Journal of Pharmacology and Experimental Therapeutics, 2018
Plasma pyridoxic acid (PDA) and homovanillic acid (HVA) were recently identified as novel endogenous biomarkers of organic anion transporter (OAT) 1/3 function in monkeys.
Hong Shen, Vinay K. Holenarsipur, T. Thanga Mariappan, Dieter M. Drexler, Joseph L. Cantone, K Prabhakar, Shashyendra Singh Gautam, Yueping Zhang, Jinping Gan, Petia Shipkova, Punit Marathe, W. Griffith Humphreys   +11 more
openalex   +2 more sources

Milk metabolome reveals pyrimidine and its degradation products as the discriminant markers of different corn silage-based nutritional strategies [PDF]

Journal of Dairy Science, 2022
: The purpose of this study was to evaluate the effect of 6 different feeding systems (based on corn silage as the main ingredient) on the chemical composition of milk and to highlight the potential of untargeted metabolomics to find discriminant marker ...
G. Rocchetti, F. Ghilardelli, E. Carboni, A.S. Atzori, F. Masoero, A. Gallo   +5 more
doaj   +3 more sources

Urinary 4-pyridoxic acid as a non-invasive biomarker for evaluating osteoarthritis severity: findings from the ROAD study

Aging Clinical and Experimental Research
Background The early detection of osteoarthritis (OA) requires reliable biomarkers; however, reports identifying such biomarkers remain limited. Aims This study aimed to evaluate the potential of urinary 4-pyridoxic acid (4PA) as a biomarker for the ...
Noriko Yoshimura, Aiko Miyazaki, Toshiko Iidaka, Nobuo Ando, Gaku Tanegashima, Shigeyuki Muraki, Hiroyuki Oka, Sakae Tanaka   +7 more
openalex   +2 more sources

Serum Pyridoxal 5′-Phosphate and 4-Pyridoxic Acid Ratio Index with Prognosis of Colorectal Cancer: A Prospective Cohort Study

Nutrients
Background: Studies on the association between serum vitamin B6 status and colorectal cancer prognosis are limited and have yielded inconsistent results.
Xue Li, Lei Xu, Qingjian Ou, Huan Xu, Yuanyuan Chen, Yu-Jing Fang, Cai‐Xia Zhang   +6 more
openalex   +2 more sources

Urinary Total Flavonoid Excretion but Not 4-Pyridoxic Acid or Potassium Can Be Used as a Biomarker for the Intake of Fruits and Vegetables

Journal of NutriLife, 2004
To gain better insight into the potential health effects of fruits and vegetables, reliable biomarkers of intake are needed. The main purpose of this study was to investigate the ability of flavonoid excretion in both 24-h and morning urine samples to ...
Kirstine Suszkiewicz Krogholm, Jóhanna Haraldsdóttir, Pia Knuthsen, Salka E. Rasmussen   +3 more
openalex   +2 more sources

Urinary 4-pyridoxic acid excretion in 24-hour versus random urine samples as a measurement of vitamin B6 status in humans

American Journal of Clinical Nutrition, 1984
Urinary excretion of 4-pyridoxic acid (4PA) in 19 men (n = 5) and women (n = 14) was measured to evaluate the validity of determining the 4PA/creatinine ratio in random urine samples as an alternative to total 24-h 4PA excretion in assessing vitamin B6 ...
K.P. Schuster, L B Bailey, J J Cerda, Jesse F. Gregory   +3 more
openalex   +2 more sources

Determination of urinary 4-pyridoxic acid using high performance liquid chromatography

American Journal of Clinical Nutrition, 1979
A high performance liquid chromatographic method is presented for the determination of the vitamin B6 metabolite, 4-pyridoxic acid, in urine. Urine samples are treated with trichloroacetic acid to precipitate protein.
Jesse F. Gregory, J. R. KIRK
openalex   +2 more sources

Vitamin B6 intakes and 24-hr 4-pyridoxic acid excretions of children

American Journal of Clinical Nutrition, 1977
Vitamin B6 intake and 4-pyridoxic acid excretions of 22 children were determined. Mean intake of vitamin B6 per day was 1.10 mg +/- 0.47. Mean percentage of vitamin B6 intake excreted as 4-pyridoxic acid was 48% +/- 23.
JS Lewis, Kieran P. Nunn
openalex   +2 more sources

Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest

American Journal of Clinical Nutrition, 1995
Vitamin B-6 metabolism in 10 volunteers during 21 d of total fasting was compared with results from 10 men consuming a diet low only in vitamin B-6 (1.76 mumol/d) and with men consuming a normal diet during bed rest.
SP Coburn, K G Thampy, HW Lane, PS Conn, P J Ziegler, DL Costill, J. Dennis Mahuren, W. J. Fink, DR Pearson, W E Schaltenbrand   +9 more
openalex   +2 more sources

The vitamin B6 requirement in oral contraceptive users II. Assessment by tryptophan metabolites, vitamin B6, and pyridoxic acid levels in urine

American Journal of Clinical Nutrition, 1979
The requirement for vitamin B6 in oral contraceptive users was studied in 8 college-age women who used combined (7) or sequential (1) oral contraceptives.
Elizabeth A. Donald, TR Bossé
openalex   +2 more sources