North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. [PDF]
, 2013 Different lifestyle patterns across Europe may influence plasma concentrations of B-vitamins and one-carbon metabolites and their relation to chronic disease. Comparison of published data on one-carbon metabolites in Western European regions is difficult
Antonia Trichopoulou +43 more
core +3 more sources
Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS) [PDF]
, 2019 BACKGROUND Acute liver rejection (ALR), a significant complication of liver transplantation, burdens patients, healthcare payers, and the healthcare providers due to an increase in morbidity, cost, and resources.
Bettcher, Lisa +11 more
core +1 more source
Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites [PDF]
, 2016 Epidemiological research has demonstrated that the consumption of red meat is an important risk factor for the development of colorectal cancer (CRC), diabetes mellitus and cardiovascular diseases.
De Smet, S. +5 more
core +2 more sources
Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains [PDF]
, 2016 Background Inadequate maternal nutrition during early fetal development can create permanent alterations in the offspring, leading to poor health outcomes.
Amy P. Murtha +5 more
core +4 more sources
Frontiers in Microbiology, 2020 Human milk is closely correlated with infant gut microbiota and is important for infant development. However, most infants receive exclusively insufficient breast milk, and the discordance between effects of commercial formula and human milk exists.
Na Li +15 more
doaj +1 more source
Effect of Astragalus membranaceus Root on the Serum Metabolome of Preweaning Dairy Calves
Agriculture, 2022 The effect of the Astragalus membranaceus root (AMR) on the serum metabolic profiles of preweaning calf were investigated in this study. Sixteen preweaning Holstein calves were randomly allocated into two groups with eight calves per group, and offered a
Li Ma +10 more
doaj +1 more source
Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin B6-Dependent Epilepsy [PDF]
, 2016 Pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, functions as a cofactor in humans for more than 140 enzymes, many of which are involved in neurotransmitter synthesis and degradation.
Champion, Mike +19 more
core +1 more source
Increased vitamin B6 turnover is associated with greater mortality risk in the general US population: A prospective biomarker study [PDF]
, 2022 Background & aims: Vitamin B6 status and mortality risk are inversely associated in different patient groups, while prospective studies in the general population are lacking.
Beyer, Anika +10 more
core +1 more source
Untargeted Metabolomics to Explore the Bacteria Exo-Metabolome Related to Plant Biostimulants
Agronomy, 2022 The control and development of plant growth promoters is a key factor for the agro-nomy industry in its economic performance. Different genera of bacteria are widely used as natural biostimulants with the aim of enhancing nutrition efficiency, abiotic ...
Carlos J. García +4 more
doaj +1 more source
Tubular Secretory Solute Clearance and HIV Infection [PDF]
, 2023 BackgroundTubular secretion is an important kidney function responsible for the clearance of numerous medications, including antibiotics and antivirals.
Abraham, Alison +13 more
core +1 more source