Results 41 to 50 of about 6,229 (253)

Inulin and Chinese Gallotannin Affect Meat Quality and Lipid Metabolism on Hu Sheep

Animals, 2022
The aim of this study was to investigate the impacts of inulin and Chinese gallotannin on the meat fatty acids and urinary metabolites in sheep. Twenty-four healthy (25.80 ± 3.85 kg) weaned Hu lambs of approximately 4.5 months old were equally divided ...
Zhaohua He, Long Cheng, Shaobin Li, Qiaoling Liu, Xue Liang, Jiang Hu, Jiqing Wang, Xiu Liu, Fangfang Zhao   +8 more
doaj   +1 more source

Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging [PDF]

, 2021
Under embargo until: 2022-06-12Background Inflammation is a key feature of aging. We aimed to (i) investigate the association of 34 blood markers potentially involved in inflammatory processes with age and mortality and (ii) develop a signature of ...
Dugué, Pierre-Antoine, English, Dallas R., Flicker, Leon, Giles, Graham G., Hodge, Allison M., Li, Sherly X., MacInnis, Robert J., Meyer, Klaus, Midttun, Øyvind, Milne, Roger L., Navionis, Anne-Sophie, Rinaldi, Sabina, Severi, Gianluca, Southey, Melissa C., Tell, Grethe S., Ueland, Per Magne, Ulvik, Arve, Vineis, Paolo   +17 more
core   +1 more source

Abnormal bile acid metabolism is an important feature of gut microbiota and fecal metabolites in patients with slow transit constipation

Frontiers in Cellular and Infection Microbiology, 2022
Destructions in the intestinal ecosystem are implicated with changes in slow transit constipation (STC), which is a kind of intractable constipation characterized by colonic motility disorder.
Yadong Fan, Chen Xu, Lulu Xie, Ying Wang, Shan Zhu, Jiren An, Yuwei Li, Zhikui Tian, Yiqi Yan, Shuang Yu, Haizhao Liu, Beitian Jia, Yiyang Wang, Li Wang, Long Yang, Long Yang, Yuhong Bian   +16 more
doaj   +1 more source

A Metabolomic Analysis of Sensitivity and Specificity of 23 Previously Proposed Biomarkers for Renal Transporter‐Mediated Drug‐Drug Interactions

Clinical Pharmacology &Therapeutics, Volume 114, Issue 5, Page 1058-1072, November 2023., 2023
Endogenous biomarkers are discussed as tools for detection of drug‐drug interactions (DDIs) mediated by renal transport proteins, such as organic cation transporter 2 (OCT2), multidrug and toxin extrusion proteins (MATE1 and MATE2‐K) and organic anion transporters (OAT1 and OAT3).
Arne Gessner, Fabian Müller, Pia Wenisch, Markus R. Heinrich, Jörg König, Peter Stopfer, Martin F. Fromm   +6 more
wiley   +1 more source

Dioscoreae Rhizoma starch improves chronic diarrhea by regulating the gut microbiotas and fecal metabolome in rats

Food Science &Nutrition, Volume 11, Issue 10, Page 6271-6287, October 2023., 2023
Yam starch alleviated the symptoms of chronic diarrhea in rats, and its effect is better than that of the water extract and crude polysaccharides of yam; it improved intestinal injury of rats with chronic diarrhea; it increased the abundance and diversity of intestinal microbiotas in rats with chronic diarrhea and regulated the abnormal intestinal ...
Qing Zhang, Xu Zhang, Qing Wang, Suiqing Chen   +3 more
wiley   +1 more source

A comparative study of the electrochemical properties of vitamin B-6 related compounds at physiological pH [PDF]

, 2011
A comparative study of vitamin B6 group and related compounds in buffered solutions using electrochemical techniques has been performed at neutral pH.
A. Pocker, A. Temizer, A.E. Braunstein, A.J. Bard, A.J. Román, A.K. Lunn, C.M. Harris, C.M. Metzler, D. Manousek, E.E. Snell, H. Lund, J. Gonzalez-Rodríguez, J. Llor, J. Llor, J. M. Sevilla, J.M. Rodríguez Mellado, J.M. RodrÍguez Mellado, J.M. RodrÍguez Mellado, J.M. RodrÍguez Mellado, L. Camacho, M. Blázquez, M. Blázquez, M. Heyrovský, M. Stanulovic, M.L. Ahrens, M.S. Ibrahim, N.P. Bazhulina, P. Zuman, P. Zuman, R. Izquierdo, R. Izquierdo, R. Schwartz, S.G. Mairanoskii, T. Pineda, T. Pineda, T. Pineda, V. Mirceski, W.F. Wolkers, Y.V. Morozov   +38 more
core   +1 more source

Stachydrine, N‐acetylornithine and trimethylamine N‐oxide levels as candidate milk biomarkers of maternal consumption of an obesogenic diet during lactation

BioFactors, Volume 49, Issue 5, Page 1022-1037, September/October 2023., 2023
Reverting to a healthy maternal diet during lactation normalizes the altered milk metabolome found in obese rats. Stachydrine, N‐acetylornithine and TMAO levels are proposed as candidate biomarkers of maternal consumption of an obesogenic diet during lactation.
Pedro Castillo, Ondrej Kuda, Jan Kopecky, Catalina Amadora Pomar, Andreu Palou, Mariona Palou, Catalina Picó   +6 more
wiley   +1 more source

The oxidation of Schiff bases of pyridoxal and pyridoxal phosphate with amino acids by manganous ions and peroxidase [PDF]

Biochemical Journal, 1966
1. Oxygen was taken up rapidly when pyridoxal or pyridoxal phosphate was added to mixtures of pea-seedling extracts and Mn(2+) ions. 2. The increases in total oxygen uptake were proportional to the pyridoxal or pyridoxal phosphate added and were accompanied by the disappearance of these compounds. 3.
Hill, J. M., Mann, P. J. G.
openaire   +2 more sources

On pathways and blind alleys—The importance of biomarkers in vitamin B6‐dependent epilepsies

Journal of Inherited Metabolic Disease, Volume 46, Issue 5, Page 839-847, September 2023., 2023
Abstract Over the past two decades, the field of vitamin B6‐dependent epilepsies has evolved by the recognition of a growing number of gene defects (ALDH7A1, PNPO, ALPL, ALDH4A1, PLPBP as well as defects of the glycosylphosphatidylinositol anchor proteins) that all lead to reduced availability of pyridoxal 5′‐phosphate, an important cofactor in ...
Barbara Plecko
wiley   +1 more source

Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS) [PDF]

, 2019
BACKGROUND Acute liver rejection (ALR), a significant complication of liver transplantation, burdens patients, healthcare payers, and the healthcare providers due to an increase in morbidity, cost, and resources.
Bettcher, Lisa, Ceballos, Brian, Ekser, Burcin, Ellensberg, Matthew, Elliott, Campbell M., Kubal, Chandrashekhar A., Maluccio, Mary A., Mangus, Richard S., Pepin, Robert, Raftery, Daniel, Saxena, Romil, Skill, Nicholas J.   +11 more
core   +1 more source