Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation. [PDF]
PLoS ONE, 2014 The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing,
Liliana Purón-Sierra +1 more
doaj +1 more source
Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]
, 2012 Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Tomasch, Miriam +3 more
core +1 more source
Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
E-Journal of Chemistry, 2010 Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug ...
V. Annapurna +3 more
doaj +1 more source
Fluids and Barriers of the CNS, 2013 Background Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs.
Shimomura Keita +6 more
doaj +1 more source
Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS. [PDF]
, 2017 Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis.
Aguilera-Lizarraga, J +10 more
core +2 more sources
Mexican Journal of Medical Research ICSA, 2013 Dysmenorrhea is one of the cyclical processes in chronic pelvic pain. Dysmenorrhea in women causes a high psychosocial and economic impact. For this reason, we conducted a study to assess the prevalence, impact and use of drugs for the treatment of ...
Héctor A. Ponce-Monter +8 more
doaj +1 more source
Rodent models of complement activation-related pseudoallergy: Inducers, symptoms, inhibitors and reaction mechanisms [PDF]
, 2015 Complement activation-related pseudoallergy (CARPA) is a hypersensitivity reaction to intravenous administration of nanoparticle-containing medicines (nanomedicines).
Dézsi, László +4 more
core +1 more source
A Simple Method for Determination of Chloropyramine in Tablets [PDF]
, 2015 A simple gas chromatography method with mass detection (GC-MS) for the determination of chloropyramine active pharmaceutical ingredient (API) in tablets was developed.
Andersson, Gerhard +3 more
core +6 more sources
Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells
Frontiers in Cell and Developmental Biology, 2022 Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma.
Roberto Berra-Romani +11 more
doaj +1 more source
Pyrilamine and O-Desmethylpyrilamine Detection in Equine Serum and Urine [PDF]
Journal of Analytical Toxicology, 2008 Pyrilamine (mepyramine) is an H1-receptor antagonist used in human and veterinary medicine. It has the potential to produce central nervous system effects in horses and therefore may have some impact on an outcome of a horse race. A single oral dose of pyrilamine (300 mg/horse) was given to three animals.
Marc, Benoit +12 more
openaire +2 more sources