Results 101 to 110 of about 197,991 (343)
Der Ursprung der Bausteine des Lebens auf der Erde im Hadaikum
Der Ursprung des Lebens im Hadaikum erforderte die Bildung von Aminosäuren und Nukleosiden als Schlüsselmoleküle des Lebens. In einer oft postulierten stark reduzierenden Atmosphäre bilden sich HCN und seine Derivate robust als plausible Ausgangsstoffe. Aber HCN bildet sich nicht in der schwach reduzierenden Atmosphäre des Hadaikums.
Nikolai Diukarev+6 more
wiley +1 more source
High-efficiency deep blue thermally activated delayed fluorescence (TADF) emitters consisting of acridan–pyrimidine donor–acceptor motifs are developed.
In Seob Park+2 more
semanticscholar +1 more source
In the title solvated compound, C24H17N5O4·C2H6OS, the solvent molecule, dimethyl sulfoxide, is linked to the title molecule by an N—H...O hydrogen bond. The pyridine ring adopts a twist-boat conformation.
P. Seethalakshmi, C. Palanivel
doaj +1 more source
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli+2 more
wiley +1 more source
In this study, novel pyrazole, imidazole, pyrimidine derivatives bearing imidazo[4,5-b]indol moiety were successfully synthesized and their chemical structures were identified and confirmed by different spectral techniques.
Nadia Ali Ahmed Elkanzi+2 more
doaj +1 more source
Antiviral Activity of 4'-thioIDU and Thymidine Analogs against Orthopoxviruses
The search for effective therapies for orthopoxvirus infections has identified diverse classes of molecules with antiviral activity. Pyrimidine analogs, such as 5-iodo-2'-deoxyuridine (idoxuridine, IDU) were among the first compounds identified with ...
Mark N. Prichard, Earl R. Kern
doaj +1 more source
Studies on the Physiology of Pyrimidines. The Metabolism of the Pyrimidine Nucleosides
The results of previous work by one of us1 indicated that the pyrimidines uracil and thymine, when fed in small amounts to dogs, are to a large extent metabolized. In the case of cytosine it was found that this substance was not utilized. It was partly excreted unchanged, partly deaminized and excreted in the form of uracil.These experiments were ...
O. H. Emerson, L. R. Cerecedo
openaire +2 more sources
We report the modular synthesis of unsaturated P5 reagents starting from triethynyl‐phosphine oxide via CuAAC. Diethynyl‐triazolyl‐phosphine oxides enable rapid, selective and stable antibody disulfide rebridging, exemplified by the generation of a potent and selective ADC. In addition, triethynyl‐phosphine oxide enables a unique single reagent peptide‐
Christian E. Stieger+5 more
wiley +1 more source
Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were
Amira Ibrahim Sayed+2 more
doaj +1 more source
A chalcone was prepared by the reaction of terephthalaldehyde with 3-acetyl-2,5-dimethylthiophene. Treatment of this chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea afforded the corresponding pyrazoline, pyrazole, and ...
Abdullah M. Asiri, Salman A. Khan
doaj +1 more source