Results 131 to 140 of about 319,341 (367)

Synthesis of Pyrimidine Fused Quinolines by Ligand-Free Copper-Catalyzed Domino Reactions.

open access: yesJournal of Organic Chemistry, 2018
Herein, we report two novel methods for the synthesis of pyrimidine fused quinolines using a one-pot C-C and C-N bond forming strategy from the reaction of 6-aminouracils with 2-bromobenzaldehydes or 2-bromobenzyl bromide derivatives in the presence of ...
Anoop Kumar Panday   +4 more
semanticscholar   +1 more source

Aromatic Diester Anolytes for Nonaqueous Redox Flow Batteries

open access: yesBatteries &Supercaps, EarlyView.
Owing to their extended π‐conjugation 2,2′‐bipyridyl aromatic diesters are stable in singly‐ and doubly‐reduced states. In a redox flow battery a high battery voltage of 2.82 V can be realized and a capacity a capacity retention of 99.5% per cycle for 260 cycles.
Nicolas Daub   +2 more
wiley   +1 more source

A Growth model for DNA evolution

open access: yes, 1996
A simple growth model for DNA evolution is introduced which is analytically solvable and reproduces the observed statistical behavior of real sequences.Comment: To be published in Europhysics ...
Herrmann, H. J., Vieira, M. de Sousa
core   +1 more source

Unlocking Biomolecule Modification with Light‐Promoted Photocatalyst‐Free Approaches: Current Tools, Challenges, and Perspectives

open access: yesChemistryEurope, EarlyView.
This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink   +3 more
wiley   +1 more source

The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α‐ACER2‐Ceramide Signaling Axis

open access: yesAdvanced Science
Metabolic abnormalities contribute to the pathogenesis of obesity and its complications. Yet, the understanding of the interactions between critical metabolic pathways that underlie obesity remains to be improved, in part owing to the lack of ...
Huiying Liu   +9 more
doaj   +1 more source

Excitation hierarchy of the quantum sine-Gordon spin chain in strong magnetic field

open access: yes, 2004
The magnetic excitation spectrum of copper pyrimidine dinitrate, a material containing S=1/2 antiferromagnetic chains with alternating g-tensor and the Dzyaloshinskii-Moriya interaction, and exhibiting a field-induced spin gap, is probed using ...
A. K. Kolezhuk   +5 more
core   +1 more source

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

open access: yesChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn   +6 more
wiley   +1 more source

Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives

open access: yesJournal of Chemistry, 2013
A series of novel N-cycloalkanes, morpholine, piperazines, pyrazole, pyrimidine, benzimidazolo[1,2-a]pyrimidine, 1,2,3,4-tetrazolo[1,5-a]pyrimidine, azopyrazolo[1,5- a]pyrimidine, pyrimido[4', 5':3,4]pyrazolo[1,5-a]pyrimidines and pyridine derivatives ...
Yuh-Wen Ho, Maw Cherng Suen
doaj   +1 more source

Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion

open access: yesOncoTarget, 2017
Gemcitabine, an anti-cancer chemotherapy drug, has additionally shown the antiviral activity against a broad range of viruses and we also have previously reported its synergistic antiviral activity with ribavirin against enteroviruses.
Kyungjin Lee   +5 more
semanticscholar   +1 more source

Covalent Attachment of a Platinum(II) Complex inside DNA Duplexes

open access: yesChemistryEurope, EarlyView.
Oxidative addition is used for the site‐specific incorporation of an organometallic PtII complex as an artificial nucleobase into a DNA duplex. The platination stabilizes the duplex and confers it with phosphorescence. An organometallic phosphorescent PtII complex is introduced into DNA duplexes via oxidative addition to a tailor‐made artificial ...
Tim Schäfer   +6 more
wiley   +1 more source

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