Results 131 to 140 of about 153,260 (279)

Evaluation of hepatotoxic properties of pyrimidine derivatives

, 2022
A. L. Yasenyavskaya, А. А. Цибизова, А. А. Озеров, I. N. Tyurenkov   +3 more
openalex   +2 more sources

Diverse immunological roles of liver‐resident immune cells in liver diseases

Precision Medical Sciences, EarlyView.
Based on their origin and functional characteristics, LRICs can be classified into four categories. These cells differ in the focus of their immune functions in liver diseases, yet all exhibit the characteristic of functional bidirectionality.
Zhengyi Fan, Xinqiang Li, Peng Jiang, Dahong Teng, Jinzhen Cai   +4 more
wiley   +1 more source

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues

, 2017
Klaas Verschueren, Mathias Cobbaut, Joachim Demaerel, Lina Saadah, Arnout Voet, Johan Van Lint, Wim M. De Borggraeve   +6 more
openalex   +2 more sources

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

A green fabrication of pharmacologically relevant fused pyrimidines using recyclable caffeine-H₃PO₄ catalyst: insight into antibacterial and cytotoxic efficacy. [PDF]

RSC Adv
Bhatnagar A, Rai N, Singh NA, Jain V, Goyal J, Pemawat G.   +5 more
europepmc   +1 more source

Novel 6-5 Fused Ring Heterocycle Antifolates with Potent Antitumor Activity: Bridge Modifications and Heterocyclic Benzoyl Isosters of 2,4-Diamino-6,7-dihydro-5H-cyclopenta(d)pyrimidine Antifolate.

, 1995
Yaichiro Kotake, Tatsuo Okauchi, A Iijima, Kumiko Yoshimatsu, Hiroaki Nomura   +4 more
openalex   +2 more sources

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Anti-Toxoplasma activity of NBMPR is mediated through the inhibition of nucleoside and nucleobase transporters. [PDF]

Parasitol Res
Pan M, Tang SQ, Ge CC, Fan SJ, He HX, Bian MM, Shen B, Huang SY.   +7 more
europepmc   +1 more source

The Synthesis and Evaluation of New Carbocyclic Pyrrolo[2,3-d]pyrimidine Nucleoside Analogs

, 2014
Hakjune Rhee, Chul‐Hoon Lee, Jongbok Lee, Hyewon Seo, Sangeun Yoon, Ko-Woon Choi   +5 more
openalex   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source