Results 141 to 150 of about 121,011 (315)
Chemistry – A European Journal, EarlyView.We report a simple, efficient, and cost‐effective methodology for introducing amino‐modifiers into DNA and RNA using a commercially available solid support. By incorporating a base‐labile sulfonyl linker within the strand, we developed an amino‐containing tandem oligonucleotide synthesis (aTOS) methodology, which enables the introduction of multiple ...
Jagandeep S. Saraya +3 more
wiley +1 more source
Pseudo‐Ring Methodology to Control the Conformations of Macrocyclic Peptides
Chemistry – A European Journal, EarlyView.Pseudo‐ring grafts represent a powerful conformational control tool in macrocyclic peptides. “Open” and “closed” conformations can be accessed from a single building block which allow for macrocyclic peptides with unique conformations, lipophilicities and fluorescence. .
Matthew Diamandas +3 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Macro‐cycling into the near‐infrared: By incorporating two cyclometallated Pt(II) units into opposite sides of a molecular rectangle, the formation of near‐infrared‐emitting excited states that span the two units is promoted in solution, compared to the corresponding, acyclic, tweezer‐like complexes. A degree of molecular reorganization is nevertheless
Rebecca J. Salthouse +4 more
wiley +1 more source
INCORPORATION OF FORMATE-C 14 INTO THE PYRIMIDINE MOIETY OF THIAMINE, [PDF]
, 1959 Martin J. Pine, Robert Guthrie
openalex +1 more source
Light‐responsive mononucleotide coacervates
Chemistry – A European Journal, Accepted Article.Liquid‐liquid phase separation (LLPS) is central to the formation of biomolecular condensates in modern cells and is also explored as a mechanism for assembling protocells. Phase‐separated droplets provide dynamic micro‐environments that concentrate reactants, enhance reactions, and allow molecular exchange, essential for both cellular regulation and ...
Edison Rafael Jimenez Granda +4 more
wiley +1 more source
Precision Medical Sciences, Volume 11, Issue 4, Page 186-194, December 2022., 2022 Voriconazole injection of Hailing Pharmaceutical Group has achieved a breakthrough in improving the solubility of voriconazole with different excipients for the first time in China. We evaluated the pharmacokinetics (PK) and safety of single/multiple doses of voriconazole injection of Hailing Pharmaceutical Group (Test, T), a biosimilar to Vfend ...
Chunqi Huang +15 more
wiley +1 more source