Results 151 to 160 of about 290,598 (376)

BASIC ESTERS OF SUBSTITUTED PYRIMIDINE-4-CARBOXYLIC ACIDS [PDF]

, 1956
Gordon A. Grant, Carl von Seemann, Stanley O. Winthrop   +2 more
openalex   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Flowering in Fruit Trees and Annual Plants as Affected by Purines, Pyrimidines and Triiodobenzoic Acid. [PDF]

, 1959
B. Kessler, RPM Bak, A. Cohen
openalex   +1 more source

Mechanoactivated Celite as a catalyst for C‒H bond perfluoroalkylation and other radical reactions

Angewandte Chemie International Edition, Accepted Article.
Herein we report that Celite (diatomaceous earth) commonly viewed as an innocent filter aid or support material, or Earth‐abundant, non‐toxic metal oxides are efficient mechanoactivated catalysts for arene and heteroarene C‒H bond radical trifluoromethylation and pentafluoroethylation, with the activity comparable with previously reported ...
Thomas J. Hasiweder, Hoan M. Dinh, Dilip K. Pandey, Aleksandr Sorvanov, Julia Khusnutdinova   +4 more
wiley   +1 more source

RESEARCHES ON PYRIMIDINES. LXXXIV. THE TRANSFORMATION BY HYDROLYSIS OF SECONDARY PYRIMIDINE NUCLEOSIDES INTO IMIDAZOL COMBINATIONS. [PDF]

, 1917
Treat B. Johnson, Sidney E. Hadley
openalex   +1 more source

Structure of 2-Methyl-5,6,7-triphenyl-6,7-dihydropyrazolo[2,3-\u3cem\u3ea\u3c/em\u3e]pyrimidine [PDF]

, 1993
C25H21N3, Mr = 363.46, monoclinic, P21/n, a = 9.245 (2), b = 23.502 (5), c = 9.340 (2) Å, β= 103.50(3)°, V=1973.3(2) Å3, Z=4, Dx= 1.220 (2) g cm-3, λ (Mo Kα )= 0.71069 Å, μ = 0.068 cm-1, F(000) = 768, T= 292 K, R = 0.091 for 1442 unique observed ...
Desenko, S. M., Lindeman, Sergey V., Lipson, V. V., Orlov, V. D., Shishkin, O. V., Struchkov, Yuri T.   +5 more
core   +1 more source

The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α‐ACER2‐Ceramide Signaling Axis

Advanced Science
Metabolic abnormalities contribute to the pathogenesis of obesity and its complications. Yet, the understanding of the interactions between critical metabolic pathways that underlie obesity remains to be improved, in part owing to the lack of ...
Huiying Liu, Pengcheng Wang, Feng Xu, Qixing Nie, Sen Yan, Zhipeng Zhang, Yi Zhang, Changtao Jiang, Xiaomei Qin, Yanli Pang   +9 more
doaj   +1 more source

Integrated Chemoenzymatic Synthesis of the mRNA Vaccine Building Block N1‐Methylpseudouridine Triphosphate

Angewandte Chemie International Edition, Accepted Article.
Pseudouridine‐5’‐triphosphate (ΨTP) and the N1‐methylated derivative (m1ΨTP) are critical monomer building blocks of the currently used mRNA vaccines, yet efficient methods of their synthesis from readily accessible substrates remain underdeveloped. We herein report notably atom‐economic and high‐yielding biocatalytic route toward ΨTP (83% yield) and ...
Martin Pfeiffer, Leo Krammer, Johannes Zöhrer, Rolf Breinbauer, Bernd Nidetzky   +4 more
wiley   +1 more source

RESEARCHES ON PYRIMIDINES: SYNTHESIS OF CYTOSINE-5-ACETIC ACID. [FIFTY-FIRST PAPER.]¹ [PDF]

, 1911
Treat B. Johnson, Harley T. Peck, Joseph A. Ambler   +2 more
openalex   +1 more source

PYRIMIDINE NUCLEOSIDES AS PRECURSORS OF PYRIMIDINES IN POLYNUCLEOTIDES [PDF]

Journal of Biological Chemistry, 1950
E. Hammarsten, E. Hammarsten, Peter Reichard, Peter Reichard, E. Saluste, E. Saluste   +5 more
openaire   +1 more source