Results 71 to 80 of about 121,011 (315)
Continuous Flow Technology Enabling Photochemistry
Advanced Synthesis &Catalysis, Accepted Article.The merger of continuous flow technology and modern photochemistry has enabled countless applications showcasing new opportunities for chemical synthesis demonstrating improvements in selectivity, safety, sustainability and scalability. This focused review aims to highlight a selection of recently published case studies from academic and industrial ...
Ruairi Crawford, Marcus Baumann
wiley +1 more source
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019 In this study, novel pyrazole, imidazole, pyrimidine derivatives bearing imidazo[4,5-b]indol moiety were successfully synthesized and their chemical structures were identified and confirmed by different spectral techniques.
Nadia Ali Ahmed Elkanzi +2 more
doaj +1 more source
Frontiers in Chemistry, 2022 In this study, twenty novel pyrimidine derivatives bearing a 1,3,4-thiadiazole skeleton were designed and synthesized. Then their antifungal activity against Botrytis cinereal (B. cinereal), Botryosphaeria dothidea (B. dothidea), and Phomopsis sp.
Nianjuan Pan +4 more
doaj +1 more source
A Multi‐Objective Molecular Generation Method Based on Pareto Algorithm and Monte Carlo Tree Search
Advanced Science, EarlyView.Pareto Monte Carlo Tree Search Molecular Generation (PMMG), a molecular generation approach leveraging Monte Carlo Tree Search (MCTS) and Pareto algorithm, efficiently explores the Pareto front in high‐dimensional objective spaces for multi‐objective drug design.
Yifei Liu +12 more
wiley +1 more source
Purine-pyrimidine symmetry, determinative degree and DNA [PDF]
arXiv, 2000 Various symmetries connected with purine-pyrimidine content of DNA sequences are studied in terms of the intruduced determinative degree, a new characteristics of nucleotide which is connected with codon usage. A numerological explanation of CG pressure is proposed. A classification of DNA sequences is given.
arxiv
Temperature and Tautomeric Effects in High-Resolution Oxygen 1s X-ray Photoelectron Spectroscopy of Purines and Pyrimidines [PDF]
J. Chem. Phys. 161, 104303 (2024)Purines and pyrimidines, crucial building blocks in biological systems, have attracted significant interest across molecular physics, biochemistry, pharmacology, and chemistry. Extensive spectroscopies have been employed for characterization, while the temperature and potential tautomeric effects can complicate the interpretation of underlying physics ...
arxiv +1 more source
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma
Advanced Science, EarlyView.RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang +6 more
wiley +1 more source
Electron Spin Resonance in sine-Gordon spin chains in the perturbative spinon regime [PDF]
, 2005 We report the low-temperature multi-frequency ESR studies of copper pyrimidine dinitrate, a spin-1/2 antiferromagnetic chain with alternating $g$-tensor and the Dzyaloshinskii-Moriya interaction, allowing us to test a new theoretical concept proposed recently by Oshikawa and Affleck [Phys. Rev. Lett. 82, 5136 (1999)].
arxiv +1 more source
Self‐Induced A‐B‐A Structure Enables Efficient Wide‐Bandgap Perovskite Solar Cells and Tandems
Advanced Science, EarlyView.DMFP penetrates to the bottom of the perovskite, forming an A‐B‐A sandwich structure with BzMIM Br, leading to strong interactions with the perovskite. In the vertical direction, utilizing multisite coordination with Pb ions forms internal molecular bridges, which not only improves crystallographic orientation but also suppresses halide phase ...
Xixi Yu +10 more
wiley +1 more source
A Comparative Experimental and Theoretical Study on Doubly Differential Electron-Impact Ionization Cross Sections of Pyrimidine [PDF]
To provide a comprehensive data set for track structure-based simulations of radiation damage in DNA, doubly differential electron-impact ionization cross sections of pyrimidine, a building block of the nucleobases cytosine and thymine, were measured for primary electron energies between 30 eV and 1 keV as a function of emission angle and secondary ...
arxiv +1 more source