Results 121 to 130 of about 16,097 (238)
Removal of uv-induced pyrimidine dimers from the replicated and unreplicated DNA of human fibroblasts [PDF]
, 1978 Excision repair in uv irradiated human fibroblasts has been examined in portions of DNA replicating after irradiation versus those remaining unreplicated.
Waters, R.
core
Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress. [PDF]
Redox Biol, 2021 Hegedűs C +10 more
europepmc +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.Researcher highlight: Extending beyond the recently reported compound heterozygous case, we report the same TYMP c.131G>C variant in a homozygous configuration, delivering key genetic evidence for its standalone pathogenicity in MNGIE. ABSTRACT Background Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder ...
Ling Li +6 more
wiley +1 more source
DNA Backbone Conformation in Cis-Syn Pyrimidine[ ]Pyrimidine Cyclobutane Dimers
, 1980 A theoretical calculation involving minimization of energy functions was made to determine the conformation of a deoxydinucleoside monophosphate pyrimidine[ ]pyrimidine cis-syn cyclobutane dimer. Such single-stranded moieties are useful models for the in
Broyde, Suse B. +2 more
core +1 more source
Cancer Informatics, 2011 Living on earth, we are exposed to ultraviolet (UV) light as part of the solar radiation. UVB spectrum light exposure contributes to the development of skin cancer by interacting with pyrimidine pairs to create lesions called cyclobutane pyrimidine ...
Kevin A. Lease, Chris Papageorgio
doaj +1 more source
Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome
Acta Crystallographica Section D, Volume 82, Issue 6, Page 683-699, June 2026.Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges +3 more
wiley +1 more source
, 2002 Covalent analogues of pairs and triplets of nucleobases consisting of purine dimers and trimers and purine-pyrimidine conjugates connected by various types of carbon-linkers (acetylene, diacetylene, vinylene, ethylene, phenylene, benzenetriyl) are ...
Hocek, Michal
core
, 2000 The 32P-postlabeling method was applied to measure directly the levels and repair rates of specific cyclobutane pyrimidine dimers and 6–4 photoproducts in 10 basal cell carcinoma patients and 10 controls matched on age, skin type, and gender after ...
Hemminki, Kari +3 more
core +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.ABSTRACT Skin boosters are increasingly used to improve dermal quality through injectable and device‐assisted approaches; however, definitions and clinical evidence remain heterogeneous. Aims To provide an updated overview and propose a practical classification of skin boosters, including mechanisms, delivery methods, clinical outcomes, and limitations.
Kyu‐ho Yi +7 more
wiley +1 more source
, 1989 DNA photolyases catalyze the light-dependent repair of pyrimidine dimers in DNA. The results of nucleotide sequence analysis and spectroscopic studies demonstrated that photolyases from Saccharomyces cerevisiae and Escherichia coli share 37% amino acid ...
Sancar, G B, Baer, M
core +1 more source