Results 141 to 150 of about 35,554 (229)

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

open access: yesThe FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat   +7 more
wiley   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

open access: yesThe FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan   +4 more
wiley   +1 more source

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues

open access: hybrid, 2017
Klaas Verschueren   +6 more
openalex   +2 more sources

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

open access: yesInternational Journal of Cosmetic Science, EarlyView.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin   +7 more
wiley   +1 more source

Discovery of a new pyrimidine synthesis inhibitor eradicating glioblastoma-initiating cells [PDF]

open access: bronze, 2019
Smile Echizenya   +14 more
openalex   +1 more source

New alternatives in photoprotection: Preparation and evaluation of lamellar silicate derivatives and their use as sunscreens

open access: yesInternational Journal of Cosmetic Science, EarlyView.
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila   +6 more
wiley   +1 more source

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