Results 141 to 150 of about 68,807 (327)

Pyrimidine Metabolism

, 1959
E.S. Canellakis, Julian J. Jaffe, Roger Mantsavinos, J.S. Krakow   +3 more
openalex   +1 more source

A Robust Strategy for Introducing Amino‐Modifiers in Nucleic Acids: Enabling Novel Amino Tandem Oligonucleotide Synthesis in DNA and RNA

Chemistry – A European Journal, EarlyView.
We report a simple, efficient, and cost‐effective methodology for introducing amino‐modifiers into DNA and RNA using a commercially available solid support. By incorporating a base‐labile sulfonyl linker within the strand, we developed an amino‐containing tandem oligonucleotide synthesis (aTOS) methodology, which enables the introduction of multiple ...
Jagandeep S. Saraya, Nicholas G. Horton, Scott R. Sammons, Derek K. O′Flaherty   +3 more
wiley   +1 more source

Studies on Pyrimidine Derivatives. I

, 1958
Kenzo Sirakawa
openalex   +2 more sources

Pseudo‐Ring Methodology to Control the Conformations of Macrocyclic Peptides

Chemistry – A European Journal, EarlyView.
Pseudo‐ring grafts represent a powerful conformational control tool in macrocyclic peptides. “Open” and “closed” conformations can be accessed from a single building block which allow for macrocyclic peptides with unique conformations, lipophilicities and fluorescence. .
Matthew Diamandas, Yang (Daniel) Ou, Ben Zhen Huang, Andrei K. Yudin   +3 more
wiley   +1 more source

Importance of Pyrimidine Derivatives in the Growth of Group C (Lancefield) Streptococci upon a Simplified Medium

, 1944
H. J. Rogers
openalex   +1 more source

Molecular Rectangles Featuring Two Parallel NCN‐Coordinated Platinum Units: Enhancing Near‐Infrared Emission Through Excimer Formation

Chemistry – A European Journal, EarlyView.
Macro‐cycling into the near‐infrared: By incorporating two cyclometallated Pt(II) units into opposite sides of a molecular rectangle, the formation of near‐infrared‐emitting excited states that span the two units is promoted in solution, compared to the corresponding, acyclic, tweezer‐like complexes. A degree of molecular reorganization is nevertheless
Rebecca J. Salthouse, Amit Sil, Piotr Pander, Fernando B. Dias, J. A. Gareth Williams   +4 more
wiley   +1 more source

INCORPORATION OF FORMATE-C ¹⁴ INTO THE PYRIMIDINE MOIETY OF THIAMINE, [PDF]

, 1959
Martin J. Pine, Robert Guthrie
openalex   +1 more source

Light‐responsive mononucleotide coacervates

Chemistry – A European Journal, Accepted Article.
Liquid‐liquid phase separation (LLPS) is central to the formation of biomolecular condensates in modern cells and is also explored as a mechanism for assembling protocells. Phase‐separated droplets provide dynamic micro‐environments that concentrate reactants, enhance reactions, and allow molecular exchange, essential for both cellular regulation and ...
Edison Rafael Jimenez Granda, Hedi Karoui, Xavier Brilland, Jean-Christophe Baret, Nicolas Martin   +4 more
wiley   +1 more source

Pharmacokinetics, safety of a single dose and multiple doses of voriconazole injection of two formulations, in Chinese healthy volunteers

Precision Medical Sciences, Volume 11, Issue 4, Page 186-194, December 2022., 2022
Voriconazole injection of Hailing Pharmaceutical Group has achieved a breakthrough in improving the solubility of voriconazole with different excipients for the first time in China. We evaluated the pharmacokinetics (PK) and safety of single/multiple doses of voriconazole injection of Hailing Pharmaceutical Group (Test, T), a biosimilar to Vfend ...
Chunqi Huang, Yannan Wang, Yi Wu, Sisi Lin, Rui Hao, Jin Yu, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Hui Huang, Zhuoyan Wang, Ying Wang   +15 more
wiley   +1 more source

Interplay of protection and damage through intermolecular processes in the decay of electronic core holes in microsolvated organic molecules [PDF]

arXiv
Soft X-ray irradiation of molecules causes electronic core-level vacancies through photoelectronemission. In light elements, such as C, N, or O, which are abundant in the biosphere, these vacancies predominantly decay by Auger emission, leading inevitably to dissociative multiply charged states.
arxiv