Results 11 to 20 of about 68,807 (327)

Synthesis of Pyrimidines and Condensed Pyrimidines [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1973
Abstract A new one-step synthesis of pyrimidines and condensed pyrimidines by heating carboxamides or cyclic lactams with formamide in the presence of POCl3 in a sealed tube is described.
openaire   +3 more sources

Synthesis of pyrimidines using nano-NiZr4 (PO4)6 as a retrievable and robust heterogeneous catalyst [PDF]

open access: yesNanochemistry Research, 2020
Nano-NiZr4 (PO4)6 has been used as an effective and retrievable heterogeneous catalyst for the synthesis of pyrimidines through the reaction of benzaldehydes, guanidinehydrochloride and malononitrile under reflux conditions in ethanol.
Hossein Shahbazi-Alavi   +1 more
doaj   +1 more source

Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents

open access: yesBeilstein Journal of Organic Chemistry, 2020
We report that phenacyl azides are key compounds for a regiodivergent synthesis of valuable, functionalized imidazole (32–98% yield) and pyrimidine derivatives (45–88% yield), with a broad substrate scope, when using deep eutectic solvents [choline ...
Paola Vitale   +5 more
doaj   +1 more source

Medicinal attributes of pyrazolo[1,5-a]pyrimidine based scaffold derivatives targeting kinases as anticancer agents

open access: yesFuture Journal of Pharmaceutical Sciences, 2016
Pyrazolo pyrimidines are fused heterocyclic ring systems which known as bioisosteres of adenine, that are necessary for every aspect of cell life. Pyrazolo[1,5-a]pyrimidines derivatives have been explored for their inhibitory activity towards a variety ...
Nasser S.M. Ismail   +3 more
doaj   +1 more source

Downy mildew resistance and genetic variability in a wild rocket germplasm collection

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3083-3095, November/December 2022., 2022
Abstract One hundred accessions of a “core collection” of Diplotaxis tenuifolia (L.) DC. and Eruca spp. were screened at seedling stage for resistance to downy mildew. Accessions tested at the seedling stage were assigned to 0–6 interaction phenotypes.
Paula S. Coelho   +5 more
wiley   +1 more source

Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt

open access: yesBeilstein Journal of Organic Chemistry, 2020
A synthesis of fluorinated pyrimidines under mild conditions from amidine hydrochlorides and the recently described potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained.
Tobias Lucas   +2 more
doaj   +1 more source

PURINE AND PYRIMIDINE ANTAGONISM IN A PYRIMIDINE-DEFICIENT MUTANT OF NEUROSPORA [PDF]

open access: yesJournal of Biological Chemistry, 1948
The present study is concerned with the inhibition of growth of the pyrimidine-deficient Neurospora mutant, No. 1298, by the naturally occurring purine ribonucleotides and ribonucleosides. This experimentally produced strain, unlike the wild type, is unable to synthesize the pyrimidine ribonucleosides on a medium containing inorganic salts ...
Pierce, John G., Loring, Hubert S.
openaire   +3 more sources

Anticipatory banking of samples enables diagnosis of adenylosuccinase deficiency following molecular autopsy in an infant with vacuolating leukoencephalopathy

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 234-237, January 2023., 2023
Abstract Adenylosuccinase deficiency is a rare inborn error of metabolism. We present a newborn who died at 52 days of age with clinical features suggestive of severe epileptic encephalopathy and leukodystrophy of unknown cause. Post‐mortem examination showed an unusual vacuolar appearance of the brain.
Spatikha Sitaram   +11 more
wiley   +1 more source

CuO/ZnO@N-GQDs@NH2 nanocomposite as superior catalyst for the synthesis of pyrimidine-triones [PDF]

open access: yesNanochemistry Research, 2021
CuO / ZnO@N - GQDs@NH2 nanocomposite (copper (II) oxide / zinc oxide @ Nitrogen-doped graphene quantum dots @ aminated) as superior catalyst has been applied for the synthesis of pyrimidine - trions by three-component reactions of N, N ...
Hossein Shahbazi-Alavi   +2 more
doaj   +1 more source

SPIRO-PYRIMIDINES. II. CYCLOHEXANE-1,5-SPIRO-PYRIMIDINES. [PDF]

open access: yesJournal of the American Chemical Society, 1921
n ...
Dox, Arthur W., Yoder, Lester
openaire   +5 more sources

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