Results 31 to 40 of about 7,405 (269)

Synthesis of Pyrazolo[1,5-α]pyrimidinone Regioisomers [PDF]

The Journal of Organic Chemistry, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Derek Cecil Cole, Lori Krim Gavrin, Stephen D. Huhn, Gregory M. Ciszewski, Arthur Lee, Brian A. Provencher, John C. McKew, Walter W. Massefski   +7 more
openaire   +4 more sources

Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Malaria is responsible for 429,000 deaths per year worldwide, and more than 200 million cases were reported in 2015. Increasing parasite resistance has imposed restrictions to the currently available antimalarial drugs.
Kamilla Rodrigues Rogerio, Leonardo J M Carvalho, Luiza Helena Pinto Domingues, Bruno Junior Neves, José Teófilo Moreira Filho, Rosane Nora Castro, Cesare Bianco Júnior, Claudio Tadeu Daniel-Ribeiro, Carolina Horta Andrade, Cedric Stephan Graebin   +9 more
doaj   +1 more source

RECENT ADVANCES IN METAL-CATALYZED C-H FUNCTIONALIZATION OF PYRIMIDINONES, QUINAZOLINONES AND FUSED QUINAZOLINONES [PDF]

, 2018
International audienceThis review emphasises the recent developments in metal-catalyzed functionalization using direct C-H bond activation of pyrimidinones (uracils), quinazolinones and quinazolinone-based fused poly-N-heterocycles as well as metal ...
Besson, Thierry, Fruit, Corinne
core   +1 more source

Photochemistry of 1-allyl-4-aryltetrazolones in solution; structural effects on photoproduct selectivity [PDF]

, 2000
The photochemistry of tetrazolones derived from the carbocyclic allylic alcohols cyclohex-2-enol and 3-methylcyclohex-2-enol and from the natural terpene alcohol nerol was investigated in solution with the aim of assessing the effect of solvent and of ...
Al, Macedo, Battistuzzi, Gianantonio, Borsari, Marco, Jjg, Moura, M., D'Onofrio, P., Rodrigues, Sola, Marco   +6 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material

Molecules, 2012
A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material.
Abd El-Galil E. Amr, Aisha S. M. Hossan, Hanaa M. A. Abu-Melha, Mohamed A. Al-Omar   +3 more
doaj   +1 more source

Synthesis and Biological Evaluation of Thieno[3,2-d]- pyrimidinones, Thieno[3,2-d]pyrimidines and Quinazolinones: Conformationally Restricted 17b-Hydroxysteroid Dehydrogenase Type 2 (17b-HSD2) Inhibitors

Molecules, 2013
In this study, a series of conformationally restricted thieno[3,2-d]pyrimidinones, thieno[3,2-d]pyrimidines and quinazolinones was designed and synthesized with the goal of improving the biological activity as 17b-hydroxysteroid dehydrogenase type 2 ...
Rolf W. Hartmann, Enrico Perspicace, Sandrine Marchais-Oberwinkler   +2 more
doaj   +1 more source

Reactivity of Hydrazine, Some Hydrazine derivatives and Diamines toward Ethyl 2,2-Dicyano-1-aryl (or alkyl)vinylcarbamate [PDF]

, 2014
A series of pyrimidinone and dipyrimidinone derivatives 2a-c, 4a-e and 6a-f has been synthesized via the reaction between ethyl 2,2-dicyano-1-aryl(or alkyl)vinylcarbamate derivatives 1a-d and hydrazine derivatives or  diamines.
Chabchoub, Fakher, Salem, Mansour, Zribi, Fethi   +2 more
core   +1 more source

Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

Molecules, 2011
all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicyclo[2.2.2]octan-2-ol (10) were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N ...
Márta Palkó, Pál Sohár, Ferenc Fülöp   +2 more
doaj   +1 more source

Recent highlights in the synthesis of highly functionalized pyrimidines [PDF]

, 2009
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Botta, Maurizio, Radi, Marco, Schenone, Silvia   +2 more
core   +1 more source

Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

Beilstein Journal of Organic Chemistry, 2018
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established.
Mark Kelada, John M. D. Walsh, Robert W. Devine, Patrick McArdle, John C. Stephens   +4 more
doaj   +1 more source