Results 31 to 40 of about 7,606 (285)

Synthesis of Pyrazolo[1,5-α]pyrimidinone Regioisomers [PDF]

The Journal of Organic Chemistry, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Derek Cecil Cole, Lori Krim Gavrin, Stephen D. Huhn, Gregory M. Ciszewski, Arthur Lee, Brian A. Provencher, John C. McKew, Walter W. Massefski   +7 more
openaire   +4 more sources

Synthesis and Biological Evaluation of Thieno[3,2-d]- pyrimidinones, Thieno[3,2-d]pyrimidines and Quinazolinones: Conformationally Restricted 17b-Hydroxysteroid Dehydrogenase Type 2 (17b-HSD2) Inhibitors

Molecules, 2013
In this study, a series of conformationally restricted thieno[3,2-d]pyrimidinones, thieno[3,2-d]pyrimidines and quinazolinones was designed and synthesized with the goal of improving the biological activity as 17b-hydroxysteroid dehydrogenase type 2 ...
Rolf W. Hartmann, Enrico Perspicace, Sandrine Marchais-Oberwinkler   +2 more
doaj   +1 more source

Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material

Molecules, 2012
A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material.
Abd El-Galil E. Amr, Aisha S. M. Hossan, Hanaa M. A. Abu-Melha, Mohamed A. Al-Omar   +3 more
doaj   +1 more source

Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

Molecules, 2011
all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicyclo[2.2.2]octan-2-ol (10) were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N ...
Márta Palkó, Pál Sohár, Ferenc Fülöp   +2 more
doaj   +1 more source

Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

Beilstein Journal of Organic Chemistry, 2018
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established.
Mark Kelada, John M. D. Walsh, Robert W. Devine, Patrick McArdle, John C. Stephens   +4 more
doaj   +1 more source

Quinazolin-4-ones, Thienopyrimidin-4-ones and Related Compounds: New Highly Active Powdery Mildewicides [1]

CHIMIA, 2003
In this short review, new quinazolinones and thieno-pyrimidinones with outstanding powdery mildew activity are introduced. The most important inventions of two major players in this field, DuPont and Syngenta, are presented and interesting ...
Harald Walter, Ronald Zeun
doaj   +1 more source

Repair, abort, ignore? Strategies for dealing with UV damage [PDF]

, 2011
DNA repair is a prominent member of the nuclear transactions triad (replication, transcription, and repair). Sophisticated mechanisms govern the cellular process of decision-making (to repair or not to repair, to proceed with cell cycle or not and ...
Khalil, Hilal S., Tummala, Hemanth, Zhelev, Nikolai   +2 more
core   +3 more sources

Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides [PDF]

Metabolites, 2020
Recently, a rare class of nonribosomal peptides (NRPs) bearing a unique Oxepine-Pyrimidinone-Ketopiperazine (OPK) scaffold has been exclusively isolated from fungal sources. Based on the number of rings and conjugation systems on the backbone, it can be further categorized into three types A, B, and C.
Yaojie Guo, Jens C. Frisvad, Thomas O. Larsen   +2 more
openaire   +5 more sources

Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones

Journal of Asian natural products research, 2018
Dozens of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones were synthesized in a straightforward method by condensation of substituted 2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-diones or N-methyl-2H-thieno[2,3-d][1, 3 ...
L. Nie, Siquan Wang, Jianguo Cao, Feize Liu, H. Xiamuxi, H. Aisa, Guozheng Huang   +6 more
semanticscholar   +1 more source

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +1 more source