Results 41 to 50 of about 7,405 (269)

Quinazolin-4-ones, Thienopyrimidin-4-ones and Related Compounds: New Highly Active Powdery Mildewicides [1]

CHIMIA, 2003
In this short review, new quinazolinones and thieno-pyrimidinones with outstanding powdery mildew activity are introduced. The most important inventions of two major players in this field, DuPont and Syngenta, are presented and interesting ...
Harald Walter, Ronald Zeun
doaj   +1 more source

Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones

Journal of Asian natural products research, 2018
Dozens of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones were synthesized in a straightforward method by condensation of substituted 2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-diones or N-methyl-2H-thieno[2,3-d][1, 3 ...
L. Nie, Siquan Wang, Jianguo Cao, Feize Liu, H. Xiamuxi, H. Aisa, Guozheng Huang   +6 more
semanticscholar   +1 more source

Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides [PDF]

Metabolites, 2020
Recently, a rare class of nonribosomal peptides (NRPs) bearing a unique Oxepine-Pyrimidinone-Ketopiperazine (OPK) scaffold has been exclusively isolated from fungal sources. Based on the number of rings and conjugation systems on the backbone, it can be further categorized into three types A, B, and C.
Yaojie Guo, Jens C. Frisvad, Thomas O. Larsen   +2 more
openaire   +5 more sources

A Review on Five and Six-Membered Heterocyclic Compounds Targeting the Penicillin-Binding Protein 2 (PBP2A) of Methicillin-Resistant Staphylococcus aureus (MRSA)

Molecules, 2023
Staphylococcus aureus is a common human pathogen. Methicillin-resistant Staphylococcus aureus (MRSA) infections pose significant and challenging therapeutic difficulties.
Shraddha S. Ambade, Vivek Kumar Gupta, Ritesh P. Bhole, Pramod B. Khedekar, Rupesh V. Chikhale   +4 more
doaj   +1 more source

A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones as Antimicrobial Agents

Journal of Chemistry, 2016
The hitherto unknown 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 1a was synthesized. Both 1a and its 2,4 dichlorophenyl derivative 1b were utilized as building blocks for the preparation of novel class of ...
A. K. Elziaty, G. Bassioni, A. M. A. Hassan, H. A. Derbala, M. S. Abdel-Aziz   +4 more
doaj   +1 more source

Optimization of Anti-kinking Designs for Vascular Grafts Based on Supramolecular Materials

Frontiers in Materials, 2020
Synthetic vascular grafts to be applied as access grafts for hemodialysis often require anti-kinking properties. Previously, electrospun microporous vascular implants based on synthetic supramolecular materials have been shown to perform adequately as ...
Dan Jing Wu, Dan Jing Wu, Dan Jing Wu, Kim van Dongen, Kim van Dongen, Kim van Dongen, Wojciech Szymczyk, Wojciech Szymczyk, Paul J. Besseling, Ruth M. Cardinaels, Giulia Marchioli, Giulia Marchioli, Giulia Marchioli, Marcel H. P. van Genderen, Marcel H. P. van Genderen, Carlijn V. C. Bouten, Carlijn V. C. Bouten, Anthal I. P. M. Smits, Anthal I. P. M. Smits, Patricia Y. W. Dankers, Patricia Y. W. Dankers, Patricia Y. W. Dankers   +21 more
doaj   +1 more source

Microwave-assisted synthesis of chromeno[2,3-d] pyrimidinone derivatives

Arabian Journal of Chemistry, 2017
New series of 10-anilino-9-alkyl-12-aryl-10,12-dihydro-11H-benzo[5,6] chromeno [2,3-d]pyrimidin-11-ones 5(a–e) and 9-anilino-10-alkyl-7-aryl-7,9-dihydro-8H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-ones 6(a–f) were prepared in three steps with microwave ...
Aida Chaker, Ennaji Najahi, Françoise Nepveu, Fakher Chanchoub   +3 more
doaj   +1 more source

Efficient synthesis, reactions and spectral characterization of pyrazolo[4’,3’:4,5]thieno[3,2-d] pyrimidines and related heterocycles

Heterocyclic Communications, 2019
New pyrazolothienopyrimidines were synthesized. The key intermediate 4-aminothieno[2,3-c]pyrazole-5-carbonitrile 1 was converted to the chloroacetyl amino derivative 2 followed by nucleophilic substitution and Dimorth rearrangement upon treatment with ...
Zaki Remon M., Kamal El-Dean Adel M., Radwan Shaban M., Saber Ahmed F.   +3 more
doaj   +1 more source

Evaluation of Neurotropic Activity and Molecular Docking Study of New Derivatives of pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidines on the Basis of pyrano[3,4-c]pyridines

Molecules, 2022
Background: Heterocyclic compounds and their fused analogs, which contain pharmacophore fragments such as pyridine, thiophene and pyrimidine rings, are of great interest due to their broad spectrum of biological activity.
Shushanik Sh. Dashyan, Eugene V. Babaev, Ervand G. Paronikyan, Armen G. Ayvazyan, Ruzanna G. Paronikyan, Lernik S. Hunanyan   +5 more
doaj   +1 more source

Repair, abort, ignore? Strategies for dealing with UV damage [PDF]

, 2011
DNA repair is a prominent member of the nuclear transactions triad (replication, transcription, and repair). Sophisticated mechanisms govern the cellular process of decision-making (to repair or not to repair, to proceed with cell cycle or not and ...
Khalil, Hilal S., Tummala, Hemanth, Zhelev, Nikolai   +2 more
core   +2 more sources