Results 51 to 60 of about 7,405 (269)
ChemInform Abstract: Synthesis and Studies of Alkynyl Pyrimidinones as Metaphase Inhibitors. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tore Benneche+5 more
openaire +4 more sources
Mesoporous molecular sieve MCM-41 catalyzed one-pot synthesis of 3,4-dihydro-2(1H)-pyrimidinones and –thiones under solvent-free conditions [PDF]
An efficient synthesis of 3,4-dihydro-2(1H)-pyrimidinones and -thiones using MCM-41 as the catalyst from an aldehyde, β-keto ester, and urea or thiourea under solvent-free conditions is described.KEY WORDS: Biginelli reaction, Dihydropyrimidinones, MCM ...
Baghernejad, Bita+3 more
core +3 more sources
Design and Synthesis of Chemical Entities of Therapeutic Interest [PDF]
Not ...
chovatia, Prafulkumar T.
core
Synthesis of Some Thienopyrimidine Derivatives
Thioxothienopyrimidinones, alkylthio- and arylalkylthiothienopyrimidinones, thienopyrimidinones, thienopyrimidines a thienopyrimidinedione and a thienotriazolo- pyrimidinone were prepared from 2-amino-3-carboethoxy-4,5-disubstituted thiophenes and 2 ...
Hassan M. Al-Hazimi+2 more
doaj +1 more source
The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides
The synthesis of 1-(beta-D-2'-deoxyribosyl)-2-pyrimidinone (dK) and its 5-methyl derivative (d5) from 2'-deoxycytidine or 2'-deoxythymidine, respectively, via silver oxide oxidation of 4-hydrazinopyrimidines is described. The necessary hydrazine substituted pyrimidine nucleosides have been prepared by transamination of a protected cytidine derivative ...
Larry W. McLaughlin, Brian D. Gildea
openaire +4 more sources
In this study, the antinociceptive properties of 3,4-dihydro-2,6-diaryl-4-oxo-pyrimidine-5-carbonitrile derivatives 5a–i at doses of 25 and 50 mg/kg were evaluated in mice, using the abdominal constriction test.
Francisco J. B. Mendonça Junior+8 more
doaj +1 more source
Ethyl 4-(2,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate [PDF]
In the title compound, C14H14F2N2O3, the dihydropyrimidinone ring adopts a flattened boat conformation. The difluorophenyl group is disordered over two orientations with occupancies of 0.544 (3) and 0.456 (3).
Babu, M.+3 more
core +3 more sources
An efficient synthesis of 3,4-dihydro-2(1H)-pyrimidinones and -thiones using MCM-41 as the catalyst from an aldehyde, β-keto ester, and urea or thiourea under solvent-free conditions is described.
Rahim Hekmatshoar+3 more
doaj
Policyclic Pyridinones and Pyrimidinones and their Antimicrobial Activity
Novel Pyridinones and pyrimidinones are synthesized by cyclic condensation of 2‐aminopyridines, respectively 2‐aminopyrimidines and corresponding acids. Condensation of 2‐amino‐4,6‐dimethylpyridine 1a and chloroacetic acid 2a gave corresponding imidazo‐[1,2,4]‐4,6‐dimethylpyridin‐3(2H)‐one 3a, whereas cyclocondensation of 1a and malonic acid 2b, gave 6,
Pranvera Breznica‐Selmani+5 more
openaire +1 more source